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Table 2 Performance findings on body temperature between the two groups. Data are expressed as count (%) or median (25th–75th percentiles). Number of hourly available temperature at normothermia = number of hourly recorded body temperature available after normothermia has been reached

From: Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial

  IC (n = 218) SFC (n = 134)
Admission temperature, °C 35.0 [34.2–35.6] 35.3 [34.4–35.8]*
Time from Arrest to Temperature < 34 °C, hours 4.9 [3.9–6.5] 6.8 [5.1–9.0]$
Time to Temperature < 34 °C, hours 2.2 [1.1–4.0] 4.4 [2.8–7.0]$
First recorded Temperature < 34 °C, °C 33.8 [33.3–33.9] 33.6 [33.2–33.8]
Cooling Rate, °C/h 0.42 [0.19–0.81] 0.34 [0.16–0.61]
Duration of cooling, hours 40 [27–51] 28 [24–48] $
During cooling
- Mean temperature, °C 33.4 [33.1–33.8] 33.5 [33.2–33.8]
- Minimum temperature, °C 32.8 [32.5–33.0] 33.6 [32.3–32.9]*
- Maximal temperature, °C 35.2 [34.3–35.9] 35.5 [34.9–36.0]*
Temperature Variability during cooling, °C 0.65 [0.40–0.88] 0.69 [0.54–0.93]*
Patients never achieving target temperature, n (%) 16 (7) 6 (4)
Temperature outside targets, hours 7 [2–20] 5 [3–8]*
Temperature within targets, % 18 [5–36] 15 [7–27]
Patients with overcooling, n (%) 30 (14) 14 (10)
Patients with overshoot, n (%) 52 (24) 39 (29)
Early interruption of cooling, n (%) 8 (6) 6 (3)
Time to Normothermia, hours 9.3 [6.8–13.6] 7.5 [6.0–10.0]*
Rewarming Rate, °C/h 0.31 [0.22–0.44] 0.37 [0.29–0.49]*
Number of hourly available temperature at normothermia, hours 48 [24–81] 39 [18–54]
Max temperature reached during normothermia, °C 38.2 [37.8–38.6] 38.0 [37.6–38.4]
Post-TTM Fever, n (%) 137 (63) 67 (50)*
  1. IC intravascular catheter, SFC surface cooling, TTM targeted temperature management. $p < 0.001; *p < 0.05; p < 0.1