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Table 2 Performance findings on body temperature between the two groups. Data are expressed as count (%) or median (25th–75th percentiles). Number of hourly available temperature at normothermia = number of hourly recorded body temperature available after normothermia has been reached

From: Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial

 

IC (n = 218)

SFC (n = 134)

Admission temperature, °C

35.0 [34.2–35.6]

35.3 [34.4–35.8]*

Time from Arrest to Temperature < 34 °C, hours

4.9 [3.9–6.5]

6.8 [5.1–9.0]$

Time to Temperature < 34 °C, hours

2.2 [1.1–4.0]

4.4 [2.8–7.0]$

First recorded Temperature < 34 °C, °C

33.8 [33.3–33.9]

33.6 [33.2–33.8]

Cooling Rate, °C/h

0.42 [0.19–0.81]

0.34 [0.16–0.61]

Duration of cooling, hours

40 [27–51]

28 [24–48] $

During cooling

- Mean temperature, °C

33.4 [33.1–33.8]

33.5 [33.2–33.8]

- Minimum temperature, °C

32.8 [32.5–33.0]

33.6 [32.3–32.9]*

- Maximal temperature, °C

35.2 [34.3–35.9]

35.5 [34.9–36.0]*

Temperature Variability during cooling, °C

0.65 [0.40–0.88]

0.69 [0.54–0.93]*

Patients never achieving target temperature, n (%)

16 (7)

6 (4)

Temperature outside targets, hours

7 [2–20]

5 [3–8]*

Temperature within targets, %

18 [5–36]

15 [7–27]

Patients with overcooling, n (%)

30 (14)

14 (10)

Patients with overshoot, n (%)

52 (24)

39 (29)

Early interruption of cooling, n (%)

8 (6)

6 (3)

Time to Normothermia, hours

9.3 [6.8–13.6]

7.5 [6.0–10.0]*

Rewarming Rate, °C/h

0.31 [0.22–0.44]

0.37 [0.29–0.49]*

Number of hourly available temperature at normothermia, hours

48 [24–81]

39 [18–54]

Max temperature reached during normothermia, °C

38.2 [37.8–38.6]

38.0 [37.6–38.4]

Post-TTM Fever, n (%)

137 (63)

67 (50)*

  1. IC intravascular catheter, SFC surface cooling, TTM targeted temperature management. $p < 0.001; *p < 0.05; p < 0.1