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Table 1 Baseline characteristics for all patients and exposure groups

From: Associations between partial pressure of oxygen and neurological outcome in out-of-hospital cardiac arrest patients: an explorative analysis of a randomized trial

Demographic characteristics All patients
n = 869
Hyperoxemia
n = 199
Normoxemia
n = 569
Hypoxemia
n = 112
Hyper- and Hypoxemia
n = 11
Age (years) (mean, SD) 63.9 ± 12.2 64.0 ± 12.8 63.9 ± 12.1 63.6 ± 11.9 63.7 ± 15.0
Male sex no. (%) 707 (81.4) 150 (75.4) 476 (83.7) 87 (77.7) 6 (58.4)
Background no. (%)
 Chronic heart failure 55 (6.3) 16 (8.0) 33 (5.9) 7 (6.2) 1 (11.0)
 TIA or stroke 69 (8.0) 16 (7.8) 43 (7.5) 11 (9.7) 0 (0)
 Arterial hypertension 347 (40.1) 78 (39.6) 228 (40.1) 46 (41.4) 5 (48.3)
 Asthma/COPD 86 (9.9) 19 (9.7) 56 (9.9) 11 (9.8) 1 (5.3)
 Diabetes mellitus 128 (14.8) 31 (15.8) 81 (14.3) 18 (16.3) 2 (22.0)
 Previous PCI 101 (11.6) 23 (11.8) 61 (10.8) 18 (15.8) 1 (10.0)
 Previous CABG 82 (9.5) 23 (11.5) 52 (9.2) 7 (6.5) 0 (0)
Cardiac arrest characteristics
 Bystander witnessed arrest no. (%) 783 (90.1) 174 (87.6) 514 (90.4) 104 (92.8) 9 (87.6)
 Bystander CPR no. (%) 638 (73.4) 140 (70.3) 428 (75.1) 77 (69.1) 6 (61.7)
 Circulatory shock on admission no. (%) 111 (12.8) 25 (12.4) 69 (12.1) 21 (18.9) 4 (36.4)
 Prehospital intubation no. (%) 576 (67.2) 138 (69.7) 382 (68.2) 63 (57.2) 7 (62.7)
 Time to ROSC (min) (mean, SD) 30.4 ± 21.7 30.9 ± 23.0 30.0 ± 21.5 31.6 ± 19.9 34.3 ± 15.5
Characteristics on admission
 pH (mean, SD.) 7.21 ± 0.15 7.20 ± 0.2 7.20 ± 0.1 7.10 ± 0.2 7.10 ± 0.2
 PaCO2 (kPa) (mean, SD) 6.4 ± 2.0 6.1 ± 2.0 6.4 ± 1.9 7.3 ± 2.4 7.9 ± 2.6
 PaO2 (kPa) (mean, SD) 25.1 ± 17.0 49.8 ± 15.1 18.9 ± 8.3 13.7 ± 11.1 35.0 ± 19.0
 Lactate (mmol/L) (mean, SD) 6.5 ± 4.3 7.3 ± 4.1 6.0 ± 4.3 7.9 ± 4.5 10.2 ± 5.4
 BE − 5 or less (mmol/l) no. (%) 579 (71.3) 144 (78.7) 362 (67.4) 81 (78.9) 7 (75.0)
 GCS-Motor 1 no. (%) 443 (51.3) 116 (58.7) 280 (49.5) 55 (49.9) 7 (78.7)
 Sedated on arrival no. (%) 254 (29.4) 43 (21.6) 179 (31.6) 34 (31.3) 2 (16.5)
  1. % are displayed as valid percent over 20 imputations. Patients with combined exposure are also included in the separate hyperoxemia or hypoxemia exposure groups
  2. SD standard deviation, TIA transient ischemic attack, COPD chronic obstructive pulmonary disease, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, CPR cardiopulmonary resuscitation, GCS Glasgow Coma Scale, ROSC return of spontaneous circulation, PaCO2 arterial partial pressure of carbon dioxide, PaO2 arterial partial pressure of oxygen, kPa kilopascal, mmol/l millimoles per liter, BE base excess