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Table 2 Association between diuretic use and hospital mortality using an extended model approach

From: Early diuretic use and mortality in critically ill patients with vasopressor support: a propensity score-matching analysis

 

Odds ratio of diuretic use

95% confidence interval

P

Model 1

0.56

(0.47–0.67)

< 0.001

Model 2

0.62

(0.51–0.74)

< 0.001

Model 3

0.58

(0.48–0.71)

< 0.001

Model 4

0.69

(0.55–0.81)

< 0.001

Model 5

0.75

(0.62–0.91)

0.004

Model 5

0.69

(0.57–0.84)

< 0.001

  1. Adjusted covariates: Model 1 = diuretic use. Model 2 = Model 1 + (comorbidities including intracranial hemorrhage, hypertension, acute kidney injury, coronary disease and diabetes). Model 3 = Model 2 + (gender, age, biochemical indices including white blood cell count and SOFA score on ICU admission). Model 4 = Model 3 + (fluid balance within 48 h after intensive care unit admission). Model 5 = Model 4 + (proportion of patients receiving vasopressors including norepinephrine, epinephrine, dopamine, and dobutamine). Model 6 = Model 4 + (dose of vasopressors including norepinephrine, epinephrine, dopamine, and dobutamine)
  2. Note: The mean variance inflation factor was 2.58 and 2.42 and the p value of the goodness of fit was 0.99 and 0.99 for Model 5 and Model 6, respectively
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Critical Care

ISSN: 1364-8535