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Table 1 Patient characteristics at enrolment

From: Sigh maneuver to enhance assessment of fluid responsiveness during pressure support ventilation

General characteristics

Responders (n = 16)

Non-responders (n = 24)

p value

 Age (years)

72 [70–77]

64 [54–75]

0.34

 Gender (male/female)

14/2

14/10

0.07

 Body mass index (kg/m2)

24 [21–27]

24 [23–26]

0.85

 SAPS II

46 [44–49]

45 [41–48]

0.43

 Temperature (°C)

37.2 [36.8–37.4]

36.9 [36.1–37.3]

0.45

Ventilator settings (baseline)

 PEEP (cmH2O)

5.0 [5.0–7.0]

5.0 [5.0–6.3]

0.77

 Pressure support (cmH2O)

10.0 [8.8–10.0]

10.0 [10.0–10.0]

0.82

 VT (mL/kg ideal body weight)

6.8 [5.9–7.4]

7.0 [6.6–7.9]

0.34

 PaO2/FiO2 (ratio)

310 [280–354]

302 [274–330]

0.65

 RR (breaths/min)

15 [13–18]

13 [10–15]

0.02

 HR/RR ratio

6.2 [5.0–6.5]

5.9 [5.0–6.4]

0.71

Vasoactive agents, n; (μg kg− 1 min− 1)

 Norepinephrine

6; (0.2 [0.2–0.3])

7; (0.2 [0.1–0.2])

0.85

 Dopamine

2; (5.6 [4.8–5.9])

0

0.89

Acute circulatory failure origin, n; (%)

 Sepsis/septic shock

6 (37.5)

10 (41.7)

0.99

 Hypovolemia

7 (43.8)

8 (33.3)

0.53

 Trauma

0

1 (4.1)

0.99

 Intracranial diseases

3 (18.7)

5 (20.9)

0.99

  1. Data presented as median (25th–75th IQR) unless otherwise specified
  2. IQR interquartile, SAPS simplified acute physiology score, PEEP positive end-expiratory pressure, VT tidal volume, PaO2/FiO2 arterial partial pressure of oxygen/fraction of inspired oxygen, RR respiratory rate, HR heart rate