Kidney histopathology in lethal human sepsis

Table 1 Patient characteristics

	Sepsis (n = 27)	Control (n = 12)
Age (mean yearS (range))	67.9 (40–85)	59.5 (20–79)
Sex (female:male)	10:17	7:5
LOS (mean days (range))	3.6 (1–12)
Comorbidities/Medical history (n)
Hypertension	8	3
Diabetes mellitus	3	1
COPD or asthma	7	4
Coronary disease	5	1
Morbid obesity	2	0
Neurologic	3	1
Renal disease	0	0
Vascular surgery	2	0
Auto-immune disease	4	2
Neoplasms (extra-renal)	4	4
RIFLE stage^a (n)
Risk	0	n.a.
Injury	12
Failure	15
Lost renal function	0
End-stage kidney failure	0
Need for RRT: yes/no	12/15	n.a.
Biopsy time (mean minutes (range))	33 (24–150)	n.a.
Microorganisms (strains)		n.a.
Gram-positive	12
Gram-negative	23
Viral (norovirus and HIV)	2
Fungus/yeast	5

LOS Length of stay, RRT renal replacement therapy, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, n.a. not applicable
^aNumber of patients at respective stages

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