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Table 1 Patient characteristics

From: Kidney histopathology in lethal human sepsis

  Sepsis (n = 27) Control (n = 12)
Age (mean yearS (range)) 67.9 (40–85) 59.5 (20–79)
Sex (female:male) 10:17 7:5
LOS (mean days (range)) 3.6 (1–12)  
Comorbidities/Medical history (n)
 Hypertension 8 3
 Diabetes mellitus 3 1
 COPD or asthma 7 4
 Coronary disease 5 1
 Morbid obesity 2 0
 Neurologic 3 1
 Renal disease 0 0
 Vascular surgery 2 0
 Auto-immune disease 4 2
 Neoplasms (extra-renal) 4 4
RIFLE stagea (n)
 Risk 0 n.a.
 Injury 12  
 Failure 15  
 Lost renal function 0  
 End-stage kidney failure 0  
Need for RRT: yes/no 12/15 n.a.
Biopsy time (mean minutes (range)) 33 (24–150) n.a.
Microorganisms (strains)   n.a.
 Gram-positive 12  
 Gram-negative 23  
 Viral (norovirus and HIV) 2  
 Fungus/yeast 5  
  1. LOS Length of stay, RRT renal replacement therapy, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, n.a. not applicable
  2. aNumber of patients at respective stages