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Table 4 Association of fluid input and mortality outcome in different profiles

From: Identification of subclasses of sepsis that showed different clinical outcomes and responses to amount of fluid resuscitation: a latent profile analysis

Variables Odds ratio Lower limit of 95% CI Upper limit of 95% CI P value
Age (each 10-year increase) 1.26 1.22 1.30 <0.001
SOFA 1.24 1.22 1.27 <0.001
ICU type (CCU as reference)
 CSRU 0.72 0.58 0.89 0.002
 MICU 1.12 0.98 1.28 0.086
 SICU 1.14 0.96 1.35 0.140
 TSICU 1.02 0.84 1.24 0.840
 RRT (yes as reference) 0.74 0.63 0.88 <0.001
Admission type (elective surgery as reference)
 Emergency 1.85 1.47 2.34 <0.001
 Urgent 1.60 1.13 2.28 0.008
 Gender (female as reference) 1.03 0.94 1.12 0.543
Ethnicity (Asian as reference)
 Black 0.84 0.61 1.15 0.265
 Hispanic 0.86 0.58 1.27 0.451
 Unknown 2.01 1.49 2.74 <0.001
 White 1.22 0.93 1.64 0.163
 Vasopressor use (yes as reference) 0.78 0.70 0.88 <0.001
Profile (1 as reference)
 Profile 2 1.15 0.96 1.37 0.123
 Profile 3 2.16 1.88 2.47 <0.001
 Profile 4 0.94 0.82 1.07 0.359
Interaction between profile and fluid inputa
 1 0.99 0.96 1.02 0.615
 2 0.94 0.82 1.06 0.318
 3 0.89 0.83 0.95 0.046
 4 1.20 1.11 1.30 <0.001
  1. aFluid input was the cumulative fluid input for the first 48 h after intensive care unit (ICU) admission. Odds ratio of mortality was reported for each 1000-mL increase in fluid input at each level of profiles. There was statistically significant interaction between profile and cumulative fluid input. To facilitate clinical interpretation, the effect sizes (odds ratio) of fluid input within each profile were reported
  2. Abbreviations: CCU coronary artery unit, CI confidence interval, CSRU cardiac surgery recovery unit, MICU medical intensive care unit, RRT renal replacement therapy, SICU surgical intensive care unit, SOFA sequential organ failure assessment, TSICU trauma-neuro intensive care unit