Fig. 3
From: Plasma mitochondrial DNA and metabolomic alterations in severe critical illness
Circos plot of differential metabolites. Bipartite graph of metabolites significantly changed (increased or decreased) with NADH dehydrogenase 1 (ND1) mitochondrial DNA (mtDNA) ≥ 3200 copies/μl plasma. Graph connects response to ND1 mtDNA ≥ 3200 copies/μl plasma with individual increased or decreased metabolites. Width of curves indicates strength of the significance (−log10(p) value). AA Amino acid metabolites, BILE Bile acids, CARB Carbohydrates, GPC Glycerophosphocholines, GPE Glycerophosphoethanolamines, LCAC Long-chain acylcarnitines, LIPID Lipid metabolites, NUC Nucleotide metabolism, SCAC Short-chain acylcarnitines, TYR Tyrosine metabolites