An intervention to control an ICU outbreak of carbapenem-resistant Acinetobacter baumannii: long-term impact for the ICU and hospital

Table 1 Demographics and Acinetobacter baumanii prevalence in the intensive care unit and hospital before and after intervention (cases per 1000 admissions)

	Before intervention (period 1)	One year postintervention (period 2)	Two years postintervention (period 3)
ICU admissions (n)	513	516	537
Age (years)	61 ± 20.2	50 ± 21.7	59 ± 21.2
Gender (male)	277 (54%)	300 (58.1%)	306 (57%)
APACHE II score	18.3 ± 8.1	18.4 ± 8.1	18.3 ± 8.0
Median ICU length of stay (days)	3 (2–6)	3 (2–7)	3 (2–6)
ICU mortality	58 (11.3%)	52 (10%)	50 (9%)
CRAB patients
CRAB ICU acquisition^a	54.6 (n = 28)	1.9 (n = 1)^b	5.6 (n = 3)^b
CRAB carriers discharged alive from ICU to hospital wards^a	58.5 (n = 30)	1.9 (n = 1)^b	7.4 (n = 4)^b
CRAB ICU admission prevalence^a	56.5 (n = 29)	5.8 (n = 3)^b	13.0 (n = 7)^b
Median ICU length of stay (days)	13 (5–22)	7 (3–28)^c
Median time from ICU admission until CRAB acquisition (days)	7 (4–11)	4 (3–32)^c
CRAB hospital mortality	31/57 (54%)	4/4 (100%)	6/10 (60%)
Medical and surgical wards
Admissions (n)	39,444	41,006	44,113
Hospital wards CRAB prevalence^a (clinical cultures)	4.4 (n = 173)	2.4 (n = 99)^b	2.5 (n = 111)^b

Abbreviations: APACHE II Acute Physiology and Chronic Health Evaluation II, CRAB Carbapenem-resistant Acinetobacter baumanii, ICU Intensive care unit
^aCases/1000 admissions
^bp < 0.001 for comparison with preintervention period
^cOne and two years postintervention combined owing to small numbers, p = ns compared to preintervention period

ISSN: 1364-8535