Table 4 Gene Ontology analysis on common differentially expressed genes between responder and non-responder patients
GO groups | Group-adjusted P value | GO ID | GO term | Number of genes | Leading GO term | Term-adjusted P value |
|---|---|---|---|---|---|---|
Group 00 | 6.44E-05 | GO:0050663 | Cytokine secretion | 22 | x | 1.11E-02 |
Group 01 | 7.17E-05 | GO:0051248 | Negative regulation of protein metabolic process | 73 | x | 1.64E-02 |
Group 02 | 3.01E-06 | GO:0002576 | Platelet degranulation | 19 | x | 4.18E-04 |
Group 03 | 6.65E-05 | GO:0030168 | Platelet activation | 18 | x | 4.55E-02 |
Group 04 | 7.64E-05 | GO:0002237 | Response to molecule of bacterial origin | 30 | Â | 2.62E-02 |
Group 04 | 7.64E-05 | GO:0071219 | Cellular response to molecule of bacterial origin | 23 | x | 5.42E-04 |
Group 05 | 5.59E-08 | GO:0009967 | Positive regulation of signal transduction | 95 | x | 4.14E-04 |
Group 05 | 5.59E-08 | GO:1902531 | Regulation of intracellular signal transduction | 107 | Â | 2.07E-03 |
Group 06 | 1.39E-25 | GO:0006887 | Exocytosis | 106 | Â | 7.79E-24 |
Group 06 | 1.39E-25 | GO:0042119 | Neutrophil activation | 78 | Â | 7.11E-23 |
Group 06 | 1.39E-25 | GO:0045055 | Regulated exocytosis | 102 | x | 5.45E-26 |
Group 06 | 1.39E-25 | GO:0043299 | Leukocyte degranulation | 81 | Â | 1.03E-22 |
Group 06 | 1.39E-25 | GO:0043312 | Neutrophil degranulation | 77 | Â | 1.32E-22 |
Group 07 | 1.64E-06 | GO:0002253 | Activation of immune response | 54 | Â | 3.68E-04 |
Group 07 | 1.64E-06 | GO:0031349 | Positive regulation of defense response | 37 | Â | 2.91E-03 |
Group 07 | 1.64E-06 | GO:0002757 | Immune response-activating signal transduction | 47 | Â | 5.24E-03 |
Group 07 | 1.64E-06 | GO:0045088 | Regulation of innate immune response | 39 | x | 8.43E-05 |
Group 07 | 1.64E-06 | GO:0045089 | Positive regulation of innate immune response | 31 | Â | 3.38E-03 |
Group 07 | 1.64E-06 | GO:0002218 | Activation of innate immune response | 28 | Â | 4.86E-03 |