Table 2 Gene Ontology analysis in responder patients
GO groups | Group-adjusted P value | Leading GO ID | Leading GO term | Leading GO genes |
|---|---|---|---|---|
Group 00 | 6.37E-5 | GO:0001820 | Serotonin secretion | 6 |
Group 01 | 3.99E-5 | GO:0006650 | Glycerophospholipid metabolic process | 44 |
Group 02 | 4.59E-5 | GO:0042981 | Regulation of apoptotic process | 124 |
Group 03 | 7.67E-5 | GO:0043281 | Regulation of cysteine-type endopeptidase activity involved in apoptotic process | 29 |
Group 04 | 8.10E-5 | GO:0002237 | Response to molecule of bacterial origin | 40 |
Group 05 | 5.76E-5 | GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | 70 |
Group 06 | 6.17E-5 | GO:0038083 | Peptidyl-tyrosine autophosphorylation | 14 |
Group 07 | 6.05E-5 | GO:0042089 | Cytokine biosynthetic process | 20 |
Group 08, Group13 | 1.12E-7, 1.25E-16 | GO:0002696 | Positive regulation of leukocyte activation | 48 |
Group 09 | 8.82E-20 | GO:0042119 | Neutrophil activation | 92 |
Group10 | 6.79E-5 | GO:0050663 | Cytokine secretion | 30 |
Group11 | 3.85E-12 | GO:0002253 | Activation of immune response | 81 |
Group12 | 1.44E-9 | GO:0009967 | Positive regulation of signal transduction | 149 |
Group13 | 1.25E-16 | GO:0030217 | T-cell differentiation | 43 |