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Table 2 Overview of primary and secondary outcomes

From: Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

 

Early cIVADs

(n = 53)

Late cIVADs

(n = 24)

Unadjusted RR (95% CI)

P value for unadjusted RR

Adjusted RRb

(95% CI)

P value for adjusted RR

Primary outcome

 Good outcome at last follow-up

23 (44.2)a

4 (17.4)a

2.543 (0.992–6.521)

0.052

3.175 (1.273–7.918)

0.013

Secondary outcomes

 Good outcome at discharge

13 (24.5)

2 (8.3)

2.943 (0.720–12.037)

0.133

3.985 (0.874–18.161)

0.074

 In-hospital mortality

14 (26.4)

5 (20.8)

1.268 (0.515–3.119)

0.605

1.086 (0.446–2.645)

0.856

 RSE termination

45 (84.9)

21 (87.5)

0.970 (0.803–1.172)

0.970

0.980 (0.803–1.197)

0.980

 Induction of burst suppression

32 (60.4)

22 (91.7)

0.659 (0.513–0.845)

0.001

0.661 (0.507–0.861)

0.002

 Use of thiopental

9 (17.0)

11 (45.8)

0.370 (0.177–0.774)

0.008

0.446 (0.205–0.974)

0.043

 Development of SRSE

30 (56.6)

18 (75.0)

0.775 (0.543–1.050)

0.095

0.769 (0.567–1.093)

0.153

  1. aOne episode lost to follow-up
  2. bAdjusted for Status Epilepticus Severity Score and a potentially fatal etiology
  3. Data in columns 2 and 3 are number (percentage)
  4. Abbreviations: CI confidence interval, cIVAD continuous intravenous anesthetic drug, RR risk ratio, RSE refractory status epilepticus, SRSE super-refractory status epilepticus