Derivation and validation of plasma endostatin for predicting renal recovery from acute kidney injury: a prospective validation study

Table 4 Biomarkers and combination models for predicting nonrecovery from AKI

	AUC (95% CI)	Cutoff value	p value
Endostatin (ng/ml)	0.776 (0.654–0.892)	63.7	< 0.001
NGAL (ng/ml)	0.669 (0.524–0.795)	162.2	0.046
Cystatin C (mg/dl)	0.683 (0.537–0.806)	4.87	0.037
Clinical risk prediction model	0.782 (0.661–0.895)	0.259	< 0.001
Endostatin–clinical risk prediction model	0.887 (0.766–0.958)	0.279	< 0.001
NGAL–clinical risk prediction model	0.801 (0.707–0.926)	0.266	< 0.001
Cystatin C–clinical risk prediction model	0.796 (0.678–0.906)	0.286	< 0.001

AKI acute kidney injury, AUC area under the receiver operating characteristic, CI confidence interval, NGAL neutrophil gelatinase-associated lipocalin

ISSN: 1364-8535