Endocan, sepsis, pneumonia, and acute respiratory distress syndrome

Table 3 Diagnostic/prognostic values of endocan in sepsis

Diagnostic value	n		Cutoff point (ng/ml)	AUC	p	Corr	Reference
Sepsis	78	Endocan	1.26	0.89	< 0.01		[52]
Sepsis		PCT	0.75	0.84	< 0.01	Yes
28-day mortality		Endocan	4.37	0.91	< 0.01
28-day mortality		PCT	7.68	0.76	< 0.01	Yes
Bacteriemia	78	Endocan	1.70	0.66	0.02		[49]
Bacteriemia	78	PCT	0.12	0.56	ns	No	[49]
Bacteriemia	126	Endocan	2.05	0.83	< 0.001		[50]
Bacteriemia		PCT	0.20	0.73	< 0.001	No	[50]
Septic shock	150	Endocan	2.90	0.74	0.001		[51]
Septic shock		PCT		0.83	0.001	Yes
28-day mortality		Endocan		0.63	0.005
28-day mortality		PCT		0.58	ns
6-month mortality		Endocan		0.65	0.002
6-month mortality		PCT		0.59	ns
Organ failure on admission	60	Endocan		0.81	< 0.05		[53]
Organ failure on admission		PCT		0.79	< 0.05	ND
MODS development in 48 h		Endocan		0.67	< 0.05
MODS development in 48 h		PCT		0.75	< 0.05	ND
ICU mortality		Endocan		0.71	< 0.05
ICU mortality		PCT		0.66	ns
Septic shock	63	Endocan	3.00	0.78	< 0.02		[19]
Septic shock		PCT		0.79	< 0.02	No
30-day mortality		Endocan	5.50	0.81	< 0.02
30-day mortality		PCT			ns

AUC area under the curve, Corr existing correlation, ICU Intensive Care Unit, MODS multiorgan dysfunction syndrome, ND not determined, ns not significant, PCT procalcitonin

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