Table 1 Demographic and clinical characteristics at baseline
Characteristic | Value |
|---|---|
Age (years) | 52 (30–58) |
Sex (male/female), n (%) | 13/7 (65/35) |
Weight (kg) | 85 (71–103) |
Height (m) | 1.79 (1.7–1.85) |
BMI (kg/m2) | 26.9 (22.2–31.9) |
Sepsis onset, n (%) | |
Community-acquired | 10 (50) |
Hospital-acquired | 10 (50) |
Site of infection, n (%) | |
Lung | 11 (55) |
Abdomen | 3 (15) |
Urogenital | 1 (5) |
Soft tissue | 3 (15) |
Endocarditis | 1 (5) |
Mixed | 1 (5) |
Pathogen, n (%) | |
Gram-positive | 3 (15) |
Gram-negative | 5 (25) |
Fungi | 1 (5) |
Mixed | 5 (25) |
Not identified | 6 (30) |
APACHE II | 40.5 (35–46) |
SOFA | 18 (16–20) |
ADAMTS13 (%) | 44 (29–56.5) |
Norepinephrine dose (μg/kg/min) | 0.82 (0.61–1.17) |
Mechanical ventilation, n (%) | 19 (95) |
Oxygenation index (PaO2/FiO2) | 132 (96–229) |
Renal replacement therapy, n (%) | 13 (65) |
Organ failure, n (%) | |
Respiratory | 19 (95) |
Coagulation | 14 (70) |
Liver | 10 (50) |
Cardiovascular | 20 (100) |
Neurological | 19 (95) |
Renal | 16 (80) |
Multi organ failure, n (%) | |
Two | 0 (0) |
Three | 1 (5) |
Four | 6 (30) |
Five | 7 (35) |
Six | 6 (30) |
Immunosuppression, n (%) | 13 (65) |