Ascorbic acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
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NCT03389555
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USA
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Septic shock
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Change in SOFA score
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Vitamin C, Thiamine and Steroids in Sepsis (VICTAS)
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NCT03509350
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USA
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Sepsis with acute cardiovascular or respiratory compromise
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Vasopressor- and ventilator-free days
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Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock (HYVCTTSSS)
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NCT03258684
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China
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Sepsis or septic shock (Sepsis-3 Criteria)
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Hospital mortality
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The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
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NCT03335124
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Slovenia
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Severe sepsis or septic shock
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Hospital mortality
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Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis (ORANGES)
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NCT03422159
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USA
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Sepsis or septic shock
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Hospital mortality
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The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial (VITAMINS)
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NCT03333278
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Australia and New Zealand
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Septic shock
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Vasopressor-free days
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Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock (HYVITS)
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NCT03380507
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Qatar
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Septic shock
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Hospital mortality
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Steroids, Thiamine, and Vitamin C in Septic Shock (STACSS)
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CTRI/2018/04/013384
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India
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Septic shock
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Shock reversal
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Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock
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NCT03540628
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USA
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Septic shock
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Mortality (as compared to the study by Marik et al. [6])
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