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Table 4 Cox regression analyses for 90-day mortality

From: Permissive fluid volume in adult patients undergoing extracorporeal membrane oxygenation treatment

CFB quartiles Cardiovascular disease Non-cardiovascular disease
Unadjusted Adjusted* Unadjusted Adjusted*
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Quartile 1 1.00 (reference)   1.00 (reference)   1.00 (reference)   1.00 (reference)  
Quartile 2 1.17 (0.75–1.83) 0.496 1.27 (0.77–2.10) 0.342 0.84 (0.56–1.27) 0.407 0.79 (0.48–1.30) 0.345
Quartile 3 2.82 (1.88–4.23) < 0.001 2.58 (1.62–4.11) < 0.001 1.61 (1.11–2.34) 0.012 1.66 (1.06–2.59) 0.026
Quartile 4 2.24 (1.47–3.41) < 0.001 2.11 (1.26–3.54) 0.004 1.37 (0.93–2.02) 0.108 1.69 (1.05–2.72) 0.030
  1. CFB Cumulative fluid balance
  2. *Adjusted for age, sex, Charlson comorbidity index, Acute Physiology and Chronic Health Evaluation II score, and propensity score
  3. Propensity score was obtained by logistic regression analysis with covariables body mass index, extracorporeal membrane oxygenation (ECMO) pump time, ECMO blood flow rate, albumin, total carbon dioxide, acute kidney injury stage
  4. The 27 (3.7%) patients who were lost to follow-up were treated as censored