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Table 3 Outcome of patients according to cumulative fluid balance quartiles

From: Permissive fluid volume in adult patients undergoing extracorporeal membrane oxygenation treatment

Variables CFB quartiles Total P for trend
Quartile 1 Quartile 2 Quartile 3 Quartile 4
Cardiovascular disease
 Incident AKI (n, %) 60 (59.3) 76 (74.4) 86 (84.3) 84 (83.1) 306 (75.4) < 0.001
 CRRT treatment (n, %)* 26 (25.7) 24 (23.5) 48 (47.1) 29 (28.7) 127 (31.3) 0.114
 Days of CRRT before ECMO (days) 0 (0–1) 0 (0–1) 1 (0–1) 0 (0–2) 1 (0–1) 0.082
 ICU LOS (days)†,‡ 10 (5–16) 10 (6–18) 7 (3–14) 7 (4–14) 8 (4–15) 0.014
 90-day mortality (n, %) 35 (34.7) 43 (42.2) 71 (69.6) 58 (57.4) 207 (51.0) < 0.001
Non-cardiovascular disease
 Incident AKI (n, %) 47 (68.1) 34 (53.1) 54 (76.1) 49 (83.1) 184 (70.0) 0.011
 CRRT treatment (n, %)* 17 (21.5) 16 (20.3) 32 (40.0) 27 (34.2) 92 (29.0) 0.011
 Days of CRRT before ECMO (days) 1 (0–2) 1 (1–2) 2 (1–2) 1 (1–2) 3 (1–3) 0.483
 ICU LOS (days)†,‡ 18 (10–33) 17 (11–28) 13 (8–31) 17 (6–40) 16 (9–32) 0.239
 90-day mortality (n, %) 49 (62.0) 43 (54.4) 63 (78.8) 54 (68.4) 209 (65.9) 0.069
  1. Abbreviations: AKI Acute kidney injury, CFB Cumulative fluid balance, CRRT Continuous renal replacement therapy, ECMO Extracorporeal membrane oxygenation, ICU Intensive care unit, LOS Length of stay
  2. *Continuous renal replacement therapy imitation during the first 3 days of ECMO commencement
  3. Data are expressed as median and IQR and compared by Jonckheere-Terpstra test
  4. LOS was presented in patients who survived at 30th day from ECMO initiation