Fig. 6
From: Angiotensin-(1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis
Histopathological studies. Light microscopy of (a) lung and (b) liver from rats that underwent sham operation (SOP), SOP plus angiotensin-(1–7) administration (1 mg/kg at 3 and 6 h after SOP procedure [SOP-Ad]), cecal ligation and puncture (CLP), and CLP plus angiotensin-(1–7) administration (CLP-Ad). Arrows indicate the infiltration of neutrophils. Hematoxylin and eosin staining showed significant necrosis in the liver at 24 h after the CLP procedure. Shown are representative micrographs from three rats per group. Magnification × 400. N = Necrotic area, cv = Central vein