From: Systematic review of incretin therapy during peri-operative and intensive care
Author, year | Threshold to define hypoglycaemia | Incretin | Comparator | Weight | Odds ratio M-H, random, 95% CI | P value | Odds ratio M-H, random, 95% CI | ||
---|---|---|---|---|---|---|---|---|---|
n | group | n | group | ||||||
Besch, 2017 [19] | 3.3 mmol L− 1 | 2 | 53 | 1 | 51 | 8.1% | 1.96 [0.17, 22.32] | 0.58 | |
Brackbill, 2012 [20] | 3.3 mmol L− 1 | 5 | 30 | 2 | 32 | 12.9% | 3.00 [0.54, 16.81] | 0.06 | |
Deane, 2010 [22] | 3.0 mmol L− 1 | 0 | 25 | 0 | 25 | Not estimable | 1 | ||
Galiatsatos, 2014 [24] | 2.8 mmol L− 1 | 1 | 9 | 3 | 9 | 7.8% | 0.25 [0.02, 3.04] | 0.58 | |
Garg, 2017 [35] | 3.9 mmol L− 1 | 1 | 33 | 1 | 33 | 5.7% | 1.00 [0.06, 16.69] | 1 | |
Holmberg, 2014 [25] | 4.0 mmol L− 1 | 8 | 21 | 0 | 41 | 6.1% | 52.26 [2.83, 966.6] | 0.003 | |
Kar, 2015 [26] | Not stated | 0 | 24 | 0 | 24 | Not estimable | 1 | ||
Kohl, 2014 [27] | 3.8 mmol L− 1 | 0 | 37 | 0 | 40 | Not estimable | 1 | ||
Lipš, 2017 [17] | 3.3 mmol L− 1 | 2 | 19 | 4 | 19 | 11.9% | 0.44 [0.07, 2.76] | 0.12 | |
Meier, 2004 [29] | 4.0 mmol L−1 | 0 | 8 | 0 | 8 | Not estimable | 1 | ||
Müssig, 2008 [31] | Not stated | 0 | 10 | 0 | 10 | Not estimable | 1 | ||
Pasquel, 2017 [33] | 3.9 mmol L−1 | 13 | 138 | 17 | 139 | 24.7% | 0.75 [0.35, 1.60] | 0.45 | |
Polderman, 2018 [18] | 4.0 mmol L−1 | 1 | 44 | 5 | 106 | 9.5% | 0.47 [0.05, 4.14] | 0.26 | |
Sokos, 2007 [34] | 3.3 mmol L−1 | 1 | 10 | 2 | 10 | 7.4% | 0.44 [0.03, 5.88] | 0.39 | |
Umpierrez, 2014 [33] | 3.9 mmol L−1 | 3 | 56 | 2 | 26 | 11.8% | 0.68 [0.11, 4.33] | 0.86 | |
Total (95% CI) | 484 | 540 | 100% | 0.97 [0.47, 2.02] | 0.94 | ||||
Total events | 37 | 37 |