|
Initial urinary cystatin C
|
Peak urinary cystatin C
|
---|
Spearman’s r
|
P value
|
Spearman’s r
|
P value
|
---|
Age, months
|
-0.230
|
<0.001
|
-0.307
|
<0.001
|
Body weight, kg
|
-0.302
|
<0.001
|
-0.389
|
<0.001
|
Male, n
|
-0.005
|
0.904
|
-0.024
|
0.589
|
Illness severitya, score
|
0.358
|
<0.001
|
0.415
|
<0.001
|
MVb, n
|
0.087
|
0.051
|
0.128
|
0.004
|
Duration of MV, days
|
0.093
|
0.035
|
0.141
|
0.001
|
AKIc, n
|
0.172
|
<0.001
|
0.164
|
<0.001
|
AKI stage
|
0.182
|
<0.001
|
0.175
|
<0.001
|
Severe AKId, n
|
0.197
|
<0.001
|
0.196
|
<0.001
|
Sepsisb, n
|
0.040
|
0.362
|
0.065
|
0.141
|
Shock/DICb, n
|
0.060
|
0.173
|
0.076
|
0.086
|
MODSb, n
|
0.102
|
0.021
|
0.122
|
0.006
|
Furosemideb, n
|
0.070
|
0.112
|
0.127
|
0.004
|
Steroidb, n
|
-0.020
|
0.655
|
-0.005
|
0.919
|
Antibioticsb, n
|
0.080
|
0.072
|
0.106
|
0.017
|
Vancomycinb, n
|
0.106
|
0.016
|
0.121
|
0.006
|
Mannitolb, n
|
-0.041
|
0.350
|
-0.070
|
0.112
|
Inotropeb, n
|
0.023
|
0.606
|
0.034
|
0.444
|
Hemofiltrationb, n
|
0.007
|
0.880
|
-0.006
|
0.898
|
- r = Spearman’s correlation coefficient
- AKI acute kidney injury, DIC disseminated intravascular coagulation, ICU intensive care unit, MODS multi-organ dysfunction syndrome, MV mechanical ventilation
- aIllness severity was assessed by the score for neonatal acute physiology in critically ill neonates and the pediatric risk of mortality III score in critically ill children
- bAdministered or developed during ICU stay
- cDeveloped during the first week after ICU admission
- dSevere AKI was defined as Kidney Disease: Improving Global Outcomes (KDIGO) stages 2 and 3