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Table 1 Baseline characteristics

From: Association between diuretics and successful discontinuation of continuous renal replacement therapy in critically ill patients with acute kidney injury

Clinical variables CRRT discontinuation group (n = 517) HD initiation group (n = 310) CRRT re-initiation group (n = 349) p value
Age (years) 62.1 (15.2) 61.0 (14.9) 61.9 (14.8) 0.613
Male 330 (63.8%) 197 (63.5%) 222 (63.6%) 0.996
Comorbidity
 Hypertension 185 (35.8%) 142 (45.8%) 95 (27.2%) < 0.001cde
 Diabetes mellitus 136 (26.3%) 94 (30.3%) 81 (23.2%) 0.118
 Ischemic heart disease 36 (7.0%) 17 (5.5%) 17 (4.9%) 0.408
 Liver cirrhosis 31 (6.0%) 24 (7.7%) 34 (9.7%) 0.123
 Heart failure 22 (4.3%) 19 (6.1%) 15 (4.3%) 0.420
At CRRT initiation
 BUN (mmol/L) 30.0 (12.1) 21.8 (10.8) 19.9 (10.8) 0.106
 Serum creatinine (μmol/L) 228.1 (145.0–351.8) 353.6 (223.7–548.1) 225.4 (147.6–337.7) < 0.001ac
 Urine output (mL/day) 570 (180–1308) 116 (0–361) 244 (32–835) < 0.001abc
Day −1 before CRRT discontinuation
 BUN (mmol/L) 13.4 (9.1) 13.6 (7.9) 13.4 (7.75) 0.924
 Serum creatinine (μmol/L) 134.4 (91.9–209.5) 191.8 (122.9–302.3) 143.2 (99.0–224.5) < 0.001ac
 Urine output (mL/day) 565 (252–1250) 45 (5–190) 60 (10–289) < 0.001ab
 Mean blood pressure (mmHg) 79.4 (15.1) 78.5 (15.4) 79.6 (15.0) 0.631
 Vasopressor use 342 (66.2%) 202 (65.2%) 241 (69.1%) 0.530
Duration of CRRT (days) 3.4 (2.6) 4.8 (5.1) 4.8 (5.0) < 0.001ab
Use of diuretics after CRRT 388 (75.0%) 129 (41.6%) 102 (29.2%) < 0.001abc
  1. Continuous variables following a normal distribution are expressed as mean (standard deviation) or median (interquartile range). Categorical variables are expressed as number (percentage). One-way analysis of variance followed by the Bonferroni correction or the Kruskal-Wallis test followed by the Mann-Whitney test was performed for analysis of the continuous renal replacement therapy (CRRT) discontinuation group versus the hemodialysis (HD) initiation group versus the CRRT re-initiation group. Categorical variables were compared using the χ2 test
  2. Abbreviations: BUN blood urea nitrogen, Day − 1 one day before CRRT discontinuation
  3. ap ≤ 0.001 for CRRT discontinuation group versus HD initiation group
  4. bp ≤ 0.001 for CRRT discontinuation group versus CRRT re-initiation group
  5. cp ≤ 0.001 for HD initiation group versus CRRT re-initiation group
  6. dp ≤ 0.01 for CRRT discontinuation group versus HD initiation group
  7. ep ≤ 0.01 for CRRT discontinuation group versus CRRT re-initiation group
  8. fp ≤ 0.01 for HD initiation group versus CRRT re-initiation group