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Table 4 Achievement of Surviving Sepsis Campaign bundle targets in 59 ICUs, Japan (n = 1184)

From: Characteristics, management, and in-hospital mortality among patients with severe sepsis in intensive care units in Japan: the FORECAST study

 

Compliance rate

Compliance with all applicable elements of sepsis 3-h bundle

 Entire 3-h resuscitation bundlea

543/844 (64.3)

 B1. Serum lactate obtained

1143/1180 (96.9)

 B2. Broad-spectrum antibiotic given

985/1179 (83.5)

 B3. Blood cultures obtained before broad-spectrum antibiotic administration

1084/1178 (92.0)

 B4. 30 mg/kg crystalloid fluid bolus delivered (yes/cases with indication)a

645/845 (76.3)

Compliance with all applicable elements of sepsis 6-h bundle

 Entire 6-h resuscitation bundleb

41/688 (3.5)

 Vasopressors use + re-measured lactate

625/752 (83.1)

 B5. Vasopressor use followed initial fluid bolus if needed to maintain MAP ≥ 65 mmHg (yes/cases with indication)

745/841 (88.6)

 B6. CVP measured (yes/cases with indication)a

225/856 (26.3)

 B7. CVP 8 mmHg achieved (yes/cases with indication)a

181/227 (79.7)

 B8. ScvO2 measured (yes/cases with indication)a

60/853 (7.0)

 B9. ScvO2 70% (or SvO2 65%) achieved (yes/cases with indication)a

49/66 (74.2)

 B10. Re-measured lactate if initial lactate elevated (yes/cases with indication)

864/960 (90.0)

 Entire 3-h resuscitation bundle + vasopressors use + re-measured lactate

397/693 (57.3)

 Entire 3-h resuscitation bundle + vasopressors use

449/750 (59.9)

  1. Reported counts (proportions). Missing data: B1 = 4, B2 = 5, B3 = 6, B4 = 9, B5 = 7, B6 = 10, B7 = 757, B8 = 9, B9 = 899, B10 = 14
  2. MAP mean arterial pressure, CVP central venous pressure, ScvO2 central venous oxygen saturation, SvO2 mixed venous oxygen saturation, ICU intensive care unit
  3. aSeptic shock or lactate > 4 mmol/L
  4. bExcluded the achievement of a CVP of 8 mmHg and a ScvO2 of 70% from the entire 6-h bundle analysis