Table 2 Demographic, infection, and admission characteristics of patients with severe sepsis (n = 1184)
Characteristics | |
|---|---|
Age at admission, years | 73 (64–81) |
Male | 719/1184 (60.7) |
BMI, kg/m2 | 22 (19–25) |
Admission source | |
 ED | 676 (57.2) |
 non-ED (hospital/department transfers) | 457 (38.7) |
 ICU | 49 (4.1) |
Coexisting conditions | |
 Myocardial infarction | 58 (4.9) |
 Congestive heart failure | 128 (10.8) |
 Peripheral vascular disease | 29 (2.4) |
 Cerebrovascular disease | 140 (11.8) |
 Dementia | 97 (8.2) |
 COPD | 82 (6.9) |
 Connective tissue disease | 83 (7.0) |
 Peptic ulcer disease | 32 (2.7) |
 Diabetes mellitus without organ damage | 197 (16.6) |
 Diabetes mellitus with organ damage | 75 (6.3) |
 Chronic kidney disease | 85 (7.2) |
 Hemiplegia | 44 (3.7) |
 Malignancy (solid) | 161 (13.6) |
 Malignancy (blood) | 23 (1.9) |
 Metastatic tumor | 26 (2.2) |
 Mild liver disease | 46 (3.9) |
 Moderate to severe liver disease | 26 (2.2) |
 AIDS | 1 (0.1) |
CCI | |
 0 | 391 (33.0) |
 1–2 | 542 (45.8) |
 3–4 | 182 (15.4) |
 > 4 | 69 (5.8) |
ADL | |
 Dependent | 288 (24.3) |
Suspected site of infection | |
 Lung | 367 (31.0) |
 Abdomen | 311 (26.3) |
 Urinary tract | 218 (18.4) |
 Soft tissue | 117 (9.9) |
 Central nervous system | 23 (1.9) |
 IV catheter | 22 (1.9) |
 Osteoarticular | 21 (1.8) |
 Endocardium | 16 (1.4) |
 Wound | 12 (1.0) |
 Implant device | 8 (0.7) |
 Other | 69 (5.8) |
Positive blood cultures | 636 (54.0) |
Septic shock | |
 Yes | 745 (62.9) |
Organ dysfunction on arrival | |
 Hypotension | 656 (55.4) |
 Hyperlactatemia (> 2 mmol/L) | 797 (67.3) |
 Acute kidney injury (Cre > 2 mg/dL) | 455 (38.4) |
 Acute lung injury | 442 (37.3) |
 Hyperbilirubinemia (> 2.0 mg/dL) | 204 (17.2) |
 Thrombocytopenia (< 100,000/μL) | 345 (29.1) |
 Coagulopathy (INR > 1.5) | 225 (19.0) |
ARDSa at 1st day | 193 (18.0) |
qSOFA score | 2 (1–3) |
qSOFA ≥ 2 | 800 (69.6) |
APACHE II score | 23 (17–29) |
SIRS score | 3 (2–4) |
SOFA score | 9 (6–11) |
SOFA score ≥ 2 | 987 (98.6) |