Table 4 Genotype and allele frequencies distribution of the IL-27 polymorphisms by different sepsis status
Sepsis subtype n (%) | Severe sepsis n (%) | Septic shock n (%) | P1 | P2 | P1* | P2* | |
|---|---|---|---|---|---|---|---|
rs153109 (−964A > G) | |||||||
AA | 42 (25.5) | 142 (39.0) | 150 (42.1) | 0.002 | 0.0002 | 0.002 | 0.0003 |
GA/GG | 123 (74.5) | 222 (61.0) | 206 (57.9) | – | – | – | – |
A | 171 (52.2) | 452 (62.1) | 453 (63.6) | 0.002 | 0.0003 | 0.002 | 0.0003 |
G | 159 (48.8) | 276 (37.9) | 259 (36.4) | – | – | – | – |
rs17855750 (2905 T > G) | |||||||
TT | 59 (73.8) | 144 (79.1) | 109 (77.3) | 0.338 | 0.552 | 0.338 | 0.711 |
GT/GG | 21 (26.2) | 38 (20.9) | 32 (22.7) | – | – | – | – |
T | 137 (85.6) | 324 (89.0) | 245 (86.9) | 0.272 | 0.711 | 0.338 | 0.711 |
G | 23 (14.4) | 40 (11.0) | 37 (13.1) | – | – | – | – |