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Table 2 sEPCR levels and polymorphism (n = 278)

From: An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU

  Global
n = 278
Non-survivors
n = 84
Survivors
n = 194
P value
sEPCR level in plasma (ng/mL)
 Day 1, n = 278 92.0 ± 54.9 102.5 ± 57.9 87.5 ± 53.0 0.0447
 Day 2, n = 261 a 91.3 ± 55.2 108.8 ± 63.9 84.6 ± 50.1 0.0047
 Delta EPCR: day 2 - day 1 −1.3 ± 24.4 4.6 ± 26.9 −3.5 ± 23.1 0.0268
EPCR A3 haplotype, n (%) (n = 259b) 38 (14.7) 10 (12.8) 28 (15.5) 0.5804
  1. Description of soluble endothelial protein C receptor (sEPCR) levels at day 1, day 2, kinetics between day 1 and day 2, and polymorphism EPCR A3 in survivors and non-survivors
  2. a17 blood samples were missing at day 2 (9 patients died before day 2, 8 sample were missing)
  3. b19 DNA samples were missing (3 patients died before DNA sample was obtained, and DNA sample was missing for 16 patients)