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Table 2 sEPCR levels and polymorphism (n = 278)

From: An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU

 

Global

n = 278

Non-survivors

n = 84

Survivors

n = 194

P value

sEPCR level in plasma (ng/mL)

 Day 1, n = 278

92.0 ± 54.9

102.5 ± 57.9

87.5 ± 53.0

0.0447

 Day 2, n = 261 a

91.3 ± 55.2

108.8 ± 63.9

84.6 ± 50.1

0.0047

 Delta EPCR: day 2 - day 1

−1.3 ± 24.4

4.6 ± 26.9

−3.5 ± 23.1

0.0268

EPCR A3 haplotype, n (%) (n = 259b)

38 (14.7)

10 (12.8)

28 (15.5)

0.5804

  1. Description of soluble endothelial protein C receptor (sEPCR) levels at day 1, day 2, kinetics between day 1 and day 2, and polymorphism EPCR A3 in survivors and non-survivors
  2. a17 blood samples were missing at day 2 (9 patients died before day 2, 8 sample were missing)
  3. b19 DNA samples were missing (3 patients died before DNA sample was obtained, and DNA sample was missing for 16 patients)