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Table 1 Population characteristics at day 1 (n = 278)

From: An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU

Population characteristics at day 1
(n = 278)
Cohort
n = 278
Non-survivors
n = 84
Survivors
n = 194
P value
Patient age (years) 64.4 ± 15.5 70.1 ± 14.5 61.9 ± 15.3 <0.0001
Male, n (%) 169 (60.8) 62 (73.8) 107 (55.2) 0.003
Body mass index (kg/m2)a 25.3 ± 5.8 25.2 ± 5.2 25.4 ± 6.1 0.791
McCabe score at day 1, n (%) 252 (90.7) 72 (85.7) 180 (92.8) 0.063
History of:
 Cardiac disease, n (%) 138 (49.6) 53 (63.1) 85 (43.8) 0.003
 Respiratory disease, n (%) 154 (55.4) 44 (52.4) 110 (56.7) 0.506
 Diabetes mellitus, n (%) 58 (20.9) 22 (23.8) 36 (18.6) 0.150
 Renal disease, n (%) 17 (6.1) 9 (10.7) 8 (4.1) 0.035
 Immunologic disease, n (%) 34 (12.2) 9 (10.7) 25 (12.9) 0.612
Fine’s score 143.9 ± 41.5 163.9 ± 35.3 135.3 ± 41.1 <0.0001
SOFA score day 1 9.8 ± 3.7 11.6 ± 4.1 9.1 ± 3.2 <0.0001
SAPS II 52.9 ± 17.7 62.6 ± 17.2 48.7 ± 16.3 <0.0001
Norepinephrine at admission, n (%) 207 (74.5) 65 (77.4) 142 (73.2) 0.462
Mechanical ventilation day 1, n (%) 199 (71.6) 71 (84 .5) 128 (65.9) 0.002
Renal replacement therapy day 1, n (%) 30 (10.8) 21 (25.0) 9 (4.6) <0.0001
Septicaemia, n (%) 117 (42.1) 38 (45.2) 79 (40.7) 0.484
Hydrocortisone, n (%) 167 (60.1) 59 (70.2) 108 (55.7) 0.023
Drotrecogin, n (%) 41 (14.8) 17 (20.2) 24 (12.4) 0.089
Length of stay (days)
 ICU 18.5 ± 19.14 16.7 ± 23.0 19.3 ± 17.2 0.298
 Hospital 28.9 ± 26.3 18.7 ± 25.8 33.5 ± 25.3 <0.0001
  1. Description of the population according to the status of patients at hospital discharge: survivors (n = 194) or non-survivors (n = 84). The mean ± standard deviation was reported for continuous variables. The number of patients in each category and the corresponding percentages are given for categorical variables. P values were obtained using chi square statistics for qualitative variables and the unpaired and two-sided Student’s t test for continuous ones
  2. SOFA Sepsis-related Organ Failure Assessment, SAPS Simplified Acute Physiology Score
  3. a19 values were missing for body mass index