Skip to main content

Table 2 Rectal colonization with resistant Gram-negative bacteria at and after ICU discharge and number of resistance phenotypes (to ceftazidime, tobramycin, colistin, meropenem and ciprofloxacin)

From: Carriage of antibiotic-resistant Gram-negative bacteria after discontinuation of selective decontamination of the digestive tract (SDD) or selective oropharyngeal decontamination (SOD)

  Number of patients colonized with ARGNB at ICU discharge Number of patients acquiring colonization with ARGNB after ICU discharge
SDD (n = 507) SOD (n = 489) p value* SDD (n = 426) SOD (n = 409) p value*
At least one AR-GNB
 ICU A 8/154 (5.2%) 29/271 (10.7%) 0.05 14/134 (10.4%) 38/224 (17.0%) 0.09
 ICU B 6/115 (5.2%) 38/124 (30.6%) < 0.0001 9/95 (9.5%) 16/96 (16.7%) 0.14
 ICU C 8/238 (3.4%) 20/94 (21.3%) < 0.0001 18/197 (9.1%) 10/89 (11.2%) 0.6
 All 22/507 (4.3%) 87/489 (17.8%) < 0.0001 41/426 (9.6%) 64/409 (15.6%) 0.01
Different ARGNB 23 97 < 0.0001 66 90 0.02
E.coli 10 46   20 36  
Enterobacter sp. 1 11   8 15  
K. pneumoniae 1 9   6 4  
P. aeruginosa 3 15   6 15  
 other 8 16   26 20  
Resistance phenotypes
 Ceftazidime 9 46   21 27  
 Ciprofloxacin 11 40   12 29  
 Tobramycin 17 33   23 36  
 Meropenem 0 3   1 3  
 Colistin 5 10   7 11  
 ESBL 7 60   20 24  
  1. ARGNB antibiotic resistant Gram-negative bacteria, SDD selective decontamination of the digestive tract, SOD selective oropharyngeal decontamination, ESBL extended spectrum beta-lactamase
  2. *p value by Chi square analysis for difference between SOD and SDD