Table 4 Complications and antibiotics
|  | No-Synbiotics (n = 37) | Synbiotics (n = 35) | p value |
|---|---|---|---|
Infectious complications, n (%) | 25 (67.6) | 10 (28.6) | < 0.05 |
 Enteritis, n (%) | 10 (27.0) | 2 (6.3) | < 0.05 |
  Onset day, median (IQR) | 15 (9–23) | 9.5 (6–13) | 0.41 |
 Ventilator-associated pneumonia, n (%) | 18 (48.6) | 5 (14.3) | < 0.05 |
  Onset day, median (IQR) | 8 (5–21) | 8 (5–13) | 0.68 |
 Bacteremia, n (%) | 5 (13.5) | 5 (14.3) | 0.92 |
Mortality, n (%) | 4 (10.8) | 3 (8.6) | 0.84 |
ICU stay, median (IQR) | 28 (17–45) | 23 (13–43) | 0.85 |
Antibiotics, n (%) | |||
 Carbapenem | 28 (75.7) | 26 (74.3) | 0.90 |
 Ampicillin/sulbactam | 18 (48.6) | 17 (48.6) | 0.99 |
 Cephalosporin | 13 (35.1) | 12 (34.3) | 0.95 |
 Vancomycin | 11 (29.7) | 11 (31.4) | 0.87 |
 Quinolone | 8 (21.6) | 12 (34.3) | 0.22 |
 Penicillin class | 5 (13.5) | 6 (17.1) | 0.66 |
Antibiotics duration (days), median (IQR) | 18 (10–28) | 13 (8–24) | 0.29 |