Table 1 Patient characteristics
| Â | No-Synbiotics | Synbiotics | p value |
|---|---|---|---|
Patients (n = 72) | 37 | 35 |  |
Age (years), median (IQR) | 74 (64–81) | 74 (64–82) | 0.73 |
Gender (male), n (%) | 22 (59) | 25 (71) | 0.29 |
APACHE II score, median (IQR) | 20 (14–26) | 19 (14–24) | 0.47 |
Comorbidities, n (%) | |||
 Heart disease | 15 (41) | 14 (40) | 0.96 |
 Diabetes mellitus | 14 (38) | 15 (43) | 0.66 |
 Immunocompromised disease | 8 (22) | 11 (31) | 0.34 |
 Malignancy | 5 (14) | 7 (20) | 0.46 |
 Chronic renal disease | 4 (11) | 5 (14) | 0.66 |
 Pulmonary disease | 3 (8) | 3 (9) | 0.94 |
Origin of sepsis, n (%) | |||
 Respiratory | 16 (43) | 19 (54) |  |
 Intra-abdominal | 4 (11) | 5 (14) |  |
 Skin/soft tissue | 4 (11) | 5 (14) |  |
 Urinary tract infection | 6 (16) | 1 (3) |  |
 CNS | 0 (0) | 2 (6) |  |
 Others | 7 (19) | 3 (9) |  |
Blood lactate, median (IQR) | 22 (14–60) | 33 (20–51) | 0.49 |