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Table 4 Multivariable analysis for hospital mortality in patients with ARDS

From: Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Variable Odds ratio (95% CI) p value
Diabetes mellitus diagnosis 1.15 (0.93, 1.42) 0.19
Age (years) 1.02 (1.02, 1.03) < 0.0001
Non-respiratory SOFA (adjusted for missing values) 1.12 (1.10, 1.49) < 0.0001
BMI (kg/m2) 0.98 (0.96, 0.99) < 0.0001
Chronic cardiac failure (NYHA III-IV) 1.36 (1.04, 1.79) 0.03
Haematologic neoplasm 4.05 (2.59, 6.36) < 0.0001
Active neoplasm 1.91 (1.43, 2.56) < 0.0001
Immunosuppression 1.56 (1.19, 2.05) 0.001
Respiratory rate (breaths/min) 1.03 (1.02, 1.04) < 0.0001
Baseline PaO2:FiO2 ratio (mmHg) 0.998 (0.997, 0.999) 0.007
Baseline PEEP (cmH2O) 0.95 (0.93, 0.98) 0.003
Baseline peak inspiratory pressure (cmH2O) 1.01 (1.00, 1.02) 0.05
Blood pH 0.18 (0.09, 0.39) < 0.0001
  1. Analysis based on data from 2633 observations
  2. Abbreviations: BMI body mass index, CI confidence interval, SOFA Sequential Organ Failure Assessment, NYHA New York heart association functional classification, PaO2:FiO2 ratio of partial pressure of arterial blood oxygen content to inspired fraction of oxygen, PEEP positive end-expiratory pressure