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Table 4 Multivariable analysis for hospital mortality in patients with ARDS

From: Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Variable

Odds ratio (95% CI)

p value

Diabetes mellitus diagnosis

1.15 (0.93, 1.42)

0.19

Age (years)

1.02 (1.02, 1.03)

< 0.0001

Non-respiratory SOFA (adjusted for missing values)

1.12 (1.10, 1.49)

< 0.0001

BMI (kg/m2)

0.98 (0.96, 0.99)

< 0.0001

Chronic cardiac failure (NYHA III-IV)

1.36 (1.04, 1.79)

0.03

Haematologic neoplasm

4.05 (2.59, 6.36)

< 0.0001

Active neoplasm

1.91 (1.43, 2.56)

< 0.0001

Immunosuppression

1.56 (1.19, 2.05)

0.001

Respiratory rate (breaths/min)

1.03 (1.02, 1.04)

< 0.0001

Baseline PaO2:FiO2 ratio (mmHg)

0.998 (0.997, 0.999)

0.007

Baseline PEEP (cmH2O)

0.95 (0.93, 0.98)

0.003

Baseline peak inspiratory pressure (cmH2O)

1.01 (1.00, 1.02)

0.05

Blood pH

0.18 (0.09, 0.39)

< 0.0001

  1. Analysis based on data from 2633 observations
  2. Abbreviations: BMI body mass index, CI confidence interval, SOFA Sequential Organ Failure Assessment, NYHA New York heart association functional classification, PaO2:FiO2 ratio of partial pressure of arterial blood oxygen content to inspired fraction of oxygen, PEEP positive end-expiratory pressure
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Critical Care

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