Table 1 Reasons why sepsis care in high-resource settings may not be comparably effective in low-resource settings
From: The global burden of sepsis: barriers and potential solutions
Populations at risk  • Poor access to preventive health care  • Unidentified and inadequately controlled comorbidities  • HIV  • Malnutrition  • Genetic features of immune response | |
Infecting pathogens  • Parasitic, viral, and mycobacterial infections  • Antimicrobial resistance  • Health care-associated infection | |
Clinical circumstances  • Limited critical care capacity  • Inadequate human resources  • Lack of large, high-quality, prospective sepsis studies in LMICs  • Insufficient implementation science research |