Table 1 Reasons why sepsis care in high-resource settings may not be comparably effective in low-resource settings
From: The global burden of sepsis: barriers and potential solutions
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Populations at risk • Poor access to preventive health care • Unidentified and inadequately controlled comorbidities • HIV • Malnutrition • Genetic features of immune response | |
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Infecting pathogens • Parasitic, viral, and mycobacterial infections • Antimicrobial resistance • Health care-associated infection | |
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Clinical circumstances • Limited critical care capacity • Inadequate human resources • Lack of large, high-quality, prospective sepsis studies in LMICs • Insufficient implementation science research |