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Table 3 Mortality, sensitivity, and specificity for different thresholds of CLIF-C ACLF score

From: Validation of CLIF-C ACLF score to define a threshold for futility of intensive care support for patients with acute-on-chronic liver failure

CLIF-C ACLF score

28-Day mortality

Sensitivity

Specificity

≥ 55

80% (95% CI 72–85)

88% (95% CI 75–95)

42% (95% CI 20–67)

≥ 60

88% (95% CI 78–94)

78% (95% CI 63–88)

74% (95% CI 49–91)

≥ 65

94% (95% CI 79–98)

59% (95% CI 44–73)

89% (95% CI 67–99)

≥ 70

100% (95% CI 78–100)

31% (95% CI 18–45)

100% (95% CI 82–100)

  1. Abbreviations: ACLF Acute-on-Chronic Liver Failure, CLIF European Foundation for the study of chronic liver failure