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Table 2 Parameters during and after extubation according to airway failure, non-airway failure and extubation success with corresponding crude odds ratios determined using multinomial logistic regression

From: Risk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures

Characteristic

Extubation success (n = 1357)

Airway failure (n = 70)

Non-airway-failure (n = 78)

 

OR

95% CI

P value

 

OR

95% CI

P value

Operator performing extubation

 Senior

368/1269 (29)

24/63 (38)

 

23/69 (33)

 

 Junior

451/1269 (36)

13/63 (21)

0.499

0.253–0.983

0.04

21/69 (30)

0.838

0.462–1.519

0.68

 Nurse

450/1269 (35)

26/63 (41)

1.129

0.637–1.999

0.56

25/69 (36)

1.125

0.628–2.015

0.69

Extubation at the end of inspiration

121/1143 (11)

8/58 (14)

1.120

0.471–2.665

0.80

7/66 (11)

1.190

0.469–3.022

0.71

Extubation at the end of expiration

108/1143 (9)

4/58 (7)

0.625

0.206–1.900

0.41

7/66 (11)

1.431

0.556–3.682

0.46

Extubation without preference

914/1143 (80)

46/58 (79)

3.422

0.465–25.197

0.23

52/66 (79)

3.869

0.527–28.414

0.18

Suctioning before extubation

1123 (83)

52 (74)

0.787

0.380–1.629

0.52

63 (81)

1.073

0.504–2.282

0.86

FiO2 set at 100% before extubation

417 (31)

21 (30)

1.294

0.732–2.289

0.38

25 (32)

1.101

0.661–1.831

0.71

Recruitment maneuvers before extubation

127 (9)

5 (7)

0.959

0.373–2.464

0.93

5 (6)

0.665

0.262–1.684

0.39

Accidental extubation

6 (0)

1 (1)

6.541

0.672–63.699

0.11

0 (0)

0.98

Self-extubation

69 (5)

5 (7)

1.436

0.560–3.681

0.45

7 (9)

1.840

0.816–4.151

0.14

Extubation protocol

441 (32)

14 (20)

0.519

0.286–0.943

0.03

24 (31)

0.923

0.563–1.513

0.75

Patient informed of extubation

1225 (90)

64 (91)

1.149

0.488–2.705

0.75

67 (86)

0.656

0.338–1.273

0.21

Daytime extubation

896 (66)

55 (79)

2.141

1.275–3.593

0.004

58 (74)

1.305

0.746–2.282

0.35

Physiotherapy

672 (50)

46 (66)

1.954

1.179–3.237

0.009

46 (59)

1.465

0.922–2.329

0.11

 Before extubation

283/672 (42)

23/46 (50)

0.792

0.341–1.840

0.59

17/46 (37)

1.171

0.383–3.582

0.78

 Between extubation and 1 h after

470/672 (70)

31/46 (67)

0.923

0.314–2.712

0.88

33/46 (72)

1.966

0.459–8.413

0.36

 More than 1 h after

236/672 (35)

12/46 (26)

0.416

0.177–0.977

0.04

22/46 (48)

2.796

0.817–9.568

0.10

Preventive NIV post extubation

290 (21)

22 (31)

1.757

0.697–4.432

0.23

28 (36)

2.237

0.905–5.527

0.08

Curative NIV post extubation

238 (18)

11 (16)

0.877

0.454–1.694

0.70

16 (21)

1.213

0.688–2.139

0.50

Inhaled corticosteroids post extubation

68 (5)

13 (19)

4.373

2.279–8.392

< 0.0001

6 (8)

1.586

0.665–3.780

0.30

Inhaled epinephrine post extubation

40 (3)

17 (24)

10.519

5.593–19.781

< 0.0001

3 (4)

1.341

0.405–4.438

0.63

  1. Data are summarized as number of extubation procedures/total number of extubation procedures (%) or median (interquartile range). All P values and ORs result from a univariate multinomial logistic regression predicting the two modalities of extubation failure (airway failure versus non-airway failure) according to the characteristics
  2. OR odds ratio, CI confidence interval, FiO2 fraction of inspired oxygen, NIV non-invasive ventilation