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Fig. 2 | Critical Care

Fig. 2

From: Risk factors and outcomes for airway failure versus non-airway failure in the intensive care unit: a multicenter observational study of 1514 extubation procedures

Fig. 2

Risk factors in the final model for predicting airway failure, non-airway failure and extubation-failure. BMI, body mass index; SOFA, sequential organ failure assessment. In the final multivariate model constructed with the 1365 extubation procedures and all available data, the main predictors of airway failure were related to patient characteristics and conditions prior to extubation: female gender (OR 2.024 (1.187–3.450), P = 0.010), baseline pathology with coma as a reason for intubation (OR 4.979 (2.797–8.864), P <£0.0001), acute respiratory failure as a reason for intubation (OR 3.395 (1.877–6.138), P < 0.0001), length of ventilation > 8 days (OR 1.956 (1.087–3.518), P = 0.025), copious secretions at the time of extubation (OR 4.066 (2.268–7.292), P < 0.0001) and absence of strong cough before extubation (OR 1.876 (1.047–3.362), P = 0.035). The main predictors of non-airway failure were also related to patient characteristics and conditions prior to extubation: non-obese status (OR 2.153 (1.052–4.408), P = 0.036), baseline pathology with coma as a reason for intubation (OR 2.177 (1.301–3.642), P = 0.003), acute respiratory failure as a reason for intubation (OR 2.067 (1.217–3.510), P = 0.0072), absence of strong cough before extubation (OR 3.240 (1.786–5.879), P = 0.0001) and a SOFA score ≥ 8 (OR 1.848 (1.100–3.105), P = 0.02)

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