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Table 2 Baseline characteristics of included patients

From: Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials

Parameter

Control group (n = 2230)

PCT group (n = 2252)

Demographics

 Age (years)

64.1 ± 15.0

63.5 ± 15.2

 Male gender

1281 (57.5%)

1273 (56.5%)

Primary focus of infection

 Respiratory

1101 (49.4%)

1102 (48.9%)

 Urinary

129 (5.8%)

118 (5.2%)

 Abdominal

417 (18.7%)

391 (17.4%)

 Skin/soft tissue

41 (1.8%)

32 (1.4%)

 CNS

35 (1.6%)

38 (1.7%)

 Other/unknown

440 (19.7%)

519 (23.0%)

 Genital/gynecologic

8 (0.4%)

3 (0.1%)

 Catheter-related

14 (0.6%)

16 (0.7%)

 Bloodstream

36 (1.6%)

25 (1.1%)

 Upper respiratory

9 (0.4%)

8 (0.4%)

Vital signs

 Temperature (°C)

37.7 ± 1.2

37.8 ± 1.1

Sepsis score

 Meeting sepsis 3 definition

1630 (73.1%)

1605 (71.3%)

 SOFA score (points)

7.4 ± 4.0

7.3 ± 4.1

Additional sepsis support

 Vasopressor use

1593 (76.3%)

1606 (76.7%)

 Ventilation support

1434 (68.1%)

1478 (69.4%)

 Renal replacement

767 (34.4%)

757 (33.6%)

  1. Values are presented as mean ± standard deviation or n (%) as appropriate
  2. CNS central nervous system, PCT procalcitonin, SD standard deviation, SOFA Sequential Organ Failure Assessment