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Table 2 Baseline characteristics of included patients

From: Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials

Parameter Control group (n = 2230) PCT group (n = 2252)
Demographics
 Age (years) 64.1 ± 15.0 63.5 ± 15.2
 Male gender 1281 (57.5%) 1273 (56.5%)
Primary focus of infection
 Respiratory 1101 (49.4%) 1102 (48.9%)
 Urinary 129 (5.8%) 118 (5.2%)
 Abdominal 417 (18.7%) 391 (17.4%)
 Skin/soft tissue 41 (1.8%) 32 (1.4%)
 CNS 35 (1.6%) 38 (1.7%)
 Other/unknown 440 (19.7%) 519 (23.0%)
 Genital/gynecologic 8 (0.4%) 3 (0.1%)
 Catheter-related 14 (0.6%) 16 (0.7%)
 Bloodstream 36 (1.6%) 25 (1.1%)
 Upper respiratory 9 (0.4%) 8 (0.4%)
Vital signs
 Temperature (°C) 37.7 ± 1.2 37.8 ± 1.1
Sepsis score
 Meeting sepsis 3 definition 1630 (73.1%) 1605 (71.3%)
 SOFA score (points) 7.4 ± 4.0 7.3 ± 4.1
Additional sepsis support
 Vasopressor use 1593 (76.3%) 1606 (76.7%)
 Ventilation support 1434 (68.1%) 1478 (69.4%)
 Renal replacement 767 (34.4%) 757 (33.6%)
  1. Values are presented as mean ± standard deviation or n (%) as appropriate
  2. CNS central nervous system, PCT procalcitonin, SD standard deviation, SOFA Sequential Organ Failure Assessment