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Table 1 Baseline characteristics of patients

From: Intravenous ivabradine versus placebo in patients with low cardiac output syndrome treated by dobutamine after elective coronary artery bypass surgery: a phase 2 exploratory randomized controlled trial

 

Ivabradine group (n = 14)

Placebo group (n = 5)

Age, years

61 [59; 67]

54 [53; 59]

Male gender, n (%)

11 (79)

5 (100)

BMI, kg/m2

27.5 [25.8; 28.9]

26.2 [25.9; 29.7]

HR, bpm

73.5 [65.0; 89.0]

75.0 [67.0; 77.0]

SBP, mm Hg

121 [112; 130]

115 [114; 125]

DBP, mm Hg

71 [66; 73]

70 [65; 75]

EuroSCORE

5.5 [4.5; 6.5]

4.0 [2.5; 7.5]

LVEF, n (%)

31.5 [25.0; 38.0]

35.0 [27.0; 39.0]

History of MI, n (%)

9 (64.0)

2 (40.0)

History of PTCA, n (%)

5 (36.0)

0 (0.0)

History of CABG, n (%)

0 (0)

0 (0)

CAD severity, n (%)

 1 vessel

0 (0)

0 (0.0)

 2 vessels

1 (7.1)

0 (0.0)

 3 or more vessels

13 (92.9)

5 (100)

Dyslipidemia, n (%)

11 (78.6)

2 (40.0)

Hypertension, n (%)

9 (64.3)

3 (60.0)

Diabetes, n (%)

7 (50.0)

2 (40.0)

Heart failure, n (%)

7 (50.0)

3 (60.0)

Beta-blocker use, n (%)

13 (92.9)

5 (100.0)

eGFR, mL/min

82 [67; 110]

82 [76; 119]

  1. Values presented as number (percentage) of patients and median [interquartile range].
  2. Abbreviations: BMI body mass index, CABG coronary artery bypass graft, CAD coronary artery disease, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate (calculated with Cockcroft-Gault formula), HR heart rate, LVEF left ventricular ejection fraction, MI myocardial infarction, PTCA percutaneous transluminal coronary angioplasty, SBP systolic blood pressure