Table 2 Ex vivo studies
From: Effects of hyperoxia on vascular tone in animal models: systematic review and meta-analysis
1st Author | Effect* | Species (strain) | Artery | Type | Tone | Model | Diameter (μm) | Vessels (n) | Oxygen** | |
|---|---|---|---|---|---|---|---|---|---|---|
Chang & Detar, 1980 [54] | ↓ | Rabbit (NZW) | Aorta | Conduit | Norepinephrine | M | 4000–5000 | 10 | 100 / | 300 |
Pittman & Graham, 1986 a [55]ǂ | ↓ | Rabbit (NZW) | Aorta | Conduit | Norepinephrine | M | nr | ? | ±100 / | 280 |
Pittman & Graham, 1986 b [55]ǂ | ↓ | Rabbit (NZW) | Aorta | Conduit | KCl | M | nr | ? | ±100 / | 280 |
Vallet et al., 1994 [56] | ↓ | Rat (SD) | Aorta | Conduit | Phenylephrine | M | 2200–2800 | 6 | 20 / | 95% |
Day et al., 1992 [51] | ↔ | Rabbit (NZW) | Aorta | Conduit | None | W | nr | 6 | 160 / | 495 |
Kwan et al., 1989 [52] | ↑ | Sheep | Coronary | Conduit | None | M | 600–2500 | 8 | 12 / | 95% |
Ngai et al., 1990 [17] | ↑ | Pig | Coronary | Conduit | None | M | nr | 10 | 20 / | 95% |
Rubanyi & Paul, 1984 b [15] | ↑ | Pig | Coronary | Conduit | Histamine | M | nr | 6 | 40 / | 95% |
Rubanyi & Paul, 1985 [18] | ↑ | Pig | Coronary | Conduit | Spontaneous/KCl | M | 1500–2000 | 10 | 12 / | 95% |
Hedegaard et al., 2011 [70] | ↓ | Pig (LY) | Coronary | Conduit | PGF2a | W | nr | 9 | 10 / | 95% |
Kalsner, 1976 [46] | ↓ | Cow | Coronary | Conduit | Spontaneous | M | nr | 14 | 112 / | 515 |
Pasgaard et al., 2007 b [53] | ↓ | Pig | Coronary | Conduit | U46199 | W | nr | 14 | 120 / | 617 |
Pasgaard et al., 2007 c [53] | ↓ | Pig | Coronary | Conduit | 5-HT | W | nr | 7 | 120 / | 617 |
Pasgaard et al., 2007 a [53] | ↔ | Pig | Coronary | Conduit | None | W | nr | ? | 120 / | 617 |
Rubanyi & Paul, 1984 a [15]ǂ | ↔ | Cow | Coronary | Conduit | KCl | M | nr | ? | 40 / | 95% |
Frisbee & Lombard, 2002 [31]# | ↓ | Rat | Cremaster | Resistance | Spontaneous | P | 140 | 12 | 10 / | 21% |
Messina et al., 1994 [13] | ↓ | Rat (WS) | Cremaster | Resistance | Spontaneous | P | 163 | 27 | 21 / | 95% |
Smit et al., 2017 b [16] | ↔ | Mouse (C57) | Femoral | Conduit | Norepinephrine | P | 293 | 16 | 78 / | 375 |
Fredricks et al., 1994 [47] | ↓ | Rat (SD) | Gracilis | Resistance | Spontaneous | P | 100–300 | 7 | 87 / | 148 |
Frisbee et al., 2001 [48] | ↓ | Rat (SD) | Gracilis | Resistance | Spontaneous | P | 185 | 15 | 15 / | 95% |
Frisbee et al., 2002 [49] | ↓ | Rat (SD) | Gracilis | Resistance | Spontaneous | P | 194 | 76 | 10 / | 21% |
Liu et al., 1997 [50] | ↓ | Rat (SD) | Gracilis | Resistance | Spontaneous | P | nr | 6 | 10 / | 21% |
Smit et al., 2017 a [16] | ↔ | Mouse (C57) | Gracilis | Resistance | Spontaneous | P | 129 | 22 | 78 / | 375 |