Carbon dioxide dynamics in relation to neurological outcome in resuscitated out-of-hospital cardiac arrest patients: an exploratory Target Temperature Management Trial substudy

Table 1 Patient baseline characteristics

Demographic characteristic	Total n = 869
Age (years), mean ± SD	63.9 ± 12.2
Male sex, n (%)	707 (81.4)
Background, n (%)
Chronic heart failure	55 (6.3)
TIA or stroke	69 (8.0)
Arterial hypertension	347 (40.1)
Asthma/COPD	86 (9.9)
Diabetes mellitus	128 (14.8)
Previous PCI	101 (11.6)
Previous CABG	82 (9.5)
Cardiac arrest characteristics
Bystander witnessed arrest, n (%)	783 (90.1)
Bystander CPR, n (%)	638 (73.4)
Shock on admission, n (%)	111 (12.8)
Prehospital intubation, n (%)	576 (67.2)
Time to ROSC (min), mean ± SD	30.4 ± 21.7
Characteristics on admission
pH	7.21 ± 0.15
PaCO₂ (kPa), mean ± SD	6.4 ± 2
PaO₂ (kPa), mean ± SD	25.1 ± 17
Lactate (mmol/L), mean ± SD	6.5 ± 4.3
BE -5 or less (mmol/l), n (%)	579 (7.3)
GCS-Motor score 1, n (%)	443 (51.3)
Sedated on arrival, n (%)	254 (29.4)

SD standard deviation, TIA transient ischemic attack, COPD chronic obstructive pulmonary disease, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, CPR cardiopulmonary resuscitation, ROSC return of spontaneous circulation, PaCO₂ arterial carbon dioxide pressure, PaO₂ arterial oxygen pressure, kPa kilopascal, BE base excess, GCS Glasgow Coma Scale

ISSN: 1364-8535