Table 5 Bias assessment for primary outcomes of included observational studies
From: Platelet storage duration and its clinical and transfusion outcomes: a systematic review
Study | Bias due to confounding | Selection bias | Bias due to classification of interventions | Deviation from protocol | Missing data | Measurement of outcomes | Selective reporting | Overall risk of bias |
|---|---|---|---|---|---|---|---|---|
Outcome: mortality | ||||||||
Welsby et al. [23] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Inaba et al. [21] | Moderate risk | Low risk | Low risk | Low risk | Unclear risk (no information) | Low to moderate risk | Moderate risk | Moderate risk |
Flint et al. [22] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Outcome: nosocomial infections | ||||||||
Juffermans et al. [24] | Moderate risk | Low risk | Low risk | Low risk | Unclear risk (no information) | Low risk | Moderate risk | Moderate risk |
Juffermans et al. [25] | Moderate risk | Low risk | Low risk | Low risk | Unclear risk (no information) | Low risk | Moderate risk | Moderate risk |
Outcome: bleeding | ||||||||
Triulzi et al. [34] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Outcome: CCI | ||||||||
Kerkhoffs et al. [32] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Dijkstra-Tiekstra et al. [28] | Serious risk | Low risk | Low risk | Low risk | Moderate risk | Low risk | Moderate risk | Serious risk |
Van Rhenen et al. [35] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Heuft et al. [33] | Serious risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk | Serious risk |
Slichter et al. [12] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Akkok et al. [31] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Heim et al. [36] | Moderate risk | Low risk | Low risk | Low risk | Unclear risk (no information) | Low risk | Moderate risk | Moderate risk |
Dijkstra-Tiekstra et al. [29] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low risk | Moderate risk | Moderate risk |
Outcome: PLT CI | ||||||||
Kaplan et al., [30] | Serious | Low risk | Low risk | Low risk | Unclear risk | Low risk | Moderate risk | Serious risk |
Outcome: TRAE | ||||||||
Kaufman et al. [4] | Moderate risk | Low risk | Low risk | Low risk | Low risk | Low to moderate risk | Moderate risk | Moderate risk |