From: Corticosteroid use and intensive care unit-acquired weakness: a systematic review and meta-analysis
Study | Study design | Country | Setting | Population | n | Examination | ICUAW | Use of CS a | ICU mortality (%)a |
---|---|---|---|---|---|---|---|---|---|
Keh et al., 2016 [18] | RCT | Germany | MSICU | Severe sepsis | 375 | Clinical | 82 | 46 vs 140 | NR |
Gupta and Mishra, 2016 [19] | Prospective cohort | India | MICU | Sepsis | 100 | EMG | 37 | 26 vs 12 | NR |
Nguyen The and Nguyen Huu, 2015 [1] | Prospective cohort | Vietnam | MSICU | ICU LOS ≥ 10 days | 133 | EMG | 73 | 29 vs 18 | 49% vs 30% |
Patel et al., 2014 [21] | Prospective cohort | America | MICU | MV ≥ 24 h | 104 | Clinical | 41 | 35 vs 44 | NR |
Wieske et al., 2014 [20] | Prospective cohort | Netherlands | MSICU | MV ≥ 2 days | 212 | Clinical | 103 | 81 vs 63 | 34% vs 9% |
Anastasopoulos et al., 2011 [22] | Prospective cohort | Greece | MSICU | ICU LOS ≥ 7 days | 190 | EMG | 40 | 28 vs 102 | 32.5% vs NR |
Sharshar et al., 2010 [23] | Prospective cohort | France | MICU, SICU | MV > 7 days | 86 | Clinical | 39 | 29 vs 22 | NR |
Brunello et al., 2010 [24] | Prospective cohort | Switzerland | MSICU | MV > 48 h and SIRS | 39 | Clinical | 13 | 4 vs 0 | 62% vs 23% |
Weber-Carstens et al., 2009 [25] | Prospective cohort | Germany | SICU | MV and SAPS II ≥ 20 | 56 | EMG | 34 | 21 vs 5 | NR |
Nanas et al., 2008 [26] | Prospective cohort | Greece | MSICU | LOS > 10 days | 185 | Clinical | 44 | 7 vs 31 | 36% vs 20% |
Ali et al., 2008 [27] | Prospective cohort | America | MICU, NICU | MV > 5days | 136 | Clinical | 35 | 16 vs 42 | 31.4% vs 6% |
Hermans et al., 2007 [28] | Prospective cohort | Belgium | MICU | MV > 7 days | 412 | EMG | 188 | 123 vs 156 | NR |
Khan et al., 2006 [30] | Prospective cohort | Canada | MSICU | Sepsis | 20 | EMG | 10 | 4 vs 4 | 55% vs 0% |
Lefaucheur et al., 2006 [29] | Prospective cohort | France | MICU | MV > 7 days, diffuse weakness | 30 | EMG | 26 | 15 vs 1 | NR |
De Jonghe et al., 2002 [31] | Prospective cohort | France | MICU, SICU | MV > 7 days and awake | 95 | Clinical | 24 | 13 vs 13 | 17% vs 6% |
de Letter et al., 2001 [33] | Prospective cohort | Netherlands | MSICU | MV ≥ 4 days | 97 | EMG | 34 | 9 vs 18 | NR |
Garnacho-Montero et al., 2001 [32] | Prospective cohort | Spain | MSICU | MV > 10 days and sepsis with MOF | 73 | EMG | 50 | 7 vs 4 | 66% vs 52% |
Coakley et al., 1998 [34] | Prospective cohort | England | MSICU | MV and ICU LOS > 7 days | 44 | EMG | 37 | 11 vs 2 | NR |