| |
Burn ≥ 50% TBSA
|
Burn ≥ 80% TBSA
|
|---|
|
Control (n = 41)
|
HVHF (n = 41)
|
p Value
|
Control (n = 21)
|
HVHF (n = 17)
|
p Value
|
|---|
|
Mortality
|
|
28-day, n (%)
|
13 (31.7)
|
9 (22.0)
|
0.46
|
10 (47.6)
|
5 (29.4)
|
0.33
|
|
60-day, n (%)
|
17 (41.5)
|
11 (26.8)
|
0.24
|
13 (61.9)
|
5 (29.4)
|
0.06
|
|
90-day, n (%)
|
19 (46.3)
|
11 (26.8)
|
0.11
|
14 (66.7)
|
5 (29.4)a
|
0.049
|
|
Sepsis, n (%)
|
21 (51.2)
|
11 (26.8)a
|
0.04
|
15 (71.4)
|
6 (37.5)a
|
0.04
|
|
Septic shock, n (%)
|
18 (43.9)
|
6 (14.6)a
|
0.01
|
13 (61.9)
|
3 (18.6)a
|
0.01
|
|
Duration of MV (days)
|
8.5 (5.3, 11.8)
|
7.0 (4.0, 10.5)
|
0.19
|
9.5 (2.5, 16.3)
|
7.0 (2.0, 8.0)
|
0.09
|
|
ICU days
|
28.5 (20.0, 48.0)
|
34.5 (15.5, 55.0)
|
0.84
|
31.0 (21.5, 47.5)
|
49.0 (18.0, 67.0)
|
0.23
|
|
Duration of vasopressors (days)
|
4.0 (2.0, 11.0)
|
1.0 (1.0, 1.0)a
|
0.001
|
8.0 (2.0, 12.5)
|
1.5 (1.0, 2.8)a
|
0.04
|
- Abbreviations: TBSA Total burn surface area, MV Mechanical ventilation, ICU Intensive care unit, HVHF High-volume haemofiltration
- Data are presented as medians (25th and 75th quantiles) or percentages. All patients were included in outcome comparisons via the intention-to-treat principle
- a p < 0.05 indicates a significant difference compared with the control group
