| Control (n = 41) | HVHF (n = 41) | p Value |
---|---|---|---|
Age (years) | 42.3 ± 12.0 | 39.6 ± 10.6 | 0.29 |
Gender (% male) | 31 (75.6) | 34 (83.0) | 0.29 |
BMI (kg/m2) | 23.7 (20.7, 25.4) | 22.0 (20.4, 25.7) | 0.46 |
TBSA (%) | 80.0 (60.0, 82.0) | 73.0 (55.0, 85.0) | 0.79 |
Full thickness area of burn, TBSA (%) | 35.0 (21.0, 49.0) | 35.0 (20.5, 58.0) | 0.70 |
ABSI | 12.0 (11.0, 13.0) | 13.0 (11.0, 14.0) | 0.81 |
Aetiology | Â | Â | 0.97 |
 Flame, n (%) | 29 (70.7) | 27 (65.9) |  |
 Scald, n (%) | 4 (9.8) | 4 (9.8) | |
 Electricity, n (%) | 7 (17.1) | 9 (22.0) | |
 Chemical, n (%) | 1 (2.4) | 1 (2.4) | |
Inhalation injury, n (%) | 24 (58.5) | 27 (65.9) | 0.82 |
Hypovolaemic shock, n (%) | 17 (41.5) | 21 (51.2) | 0.87 |
Receiving MV, n (%) | 9 (22.0) | 6 (14.6) | 0.28 |
Time of randomization (hours post-burn) | 20.0 (10.5, 44.8) | 22.0 (14.5, 31.0) | 0.37 |
Time of HVHF initiation (hours post-burn) | Â | 23.0 (15.5, 34.0) | Â |
APACHE II score | 11.0 (9.0, 13.0) | 10.0 (9.0, 13.0) | 0.51 |
SOFA score | 3.0 (2.0, 5.0) | 3.0 (1.5, 4.0) | 0.69 |
TBIL (μmol/L) | 15.2 (9.5, 26.6) | 17.0 (12.4, 23.7) | 0.54 |
BUN (mmol/L) | 7.7 (4.6, 9.7) | 6.5 (4.8, 8.6) | 0.23 |
Cr (mmol/L) | 88.0 (68.0, 132.0) | 78.0 (65.0, 106.0) | 0.38 |
Operation frequency in 28Â days post-burn | 2.0 (2.0, 2.0) | 2.0 (1.0, 3.0) | 0.55 |
Time of first excision (days post-burn) | 5.0 (4.0, 7.0) | 5.0 (3.5, 5.5) | 0.54 |
Area of first excision, TBSA (%) | 18.0 (11.0, 35.0) | 18.5 (10.0, 33.5) | 0.97 |
Total area of excision in 28Â days post-burn, TBSA (%) | 29.0 (19.0, 45.0) | 34.0 (20.0, 58.0) | 0.42 |