Skip to main content

Table 1 Baseline characteristics of patients in high-volume haemofiltration and control groups

From: Early application of continuous high-volume haemofiltration can reduce sepsis and improve the prognosis of patients with severe burns

  Control (n = 41) HVHF (n = 41) p Value
Age (years) 42.3 ± 12.0 39.6 ± 10.6 0.29
Gender (% male) 31 (75.6) 34 (83.0) 0.29
BMI (kg/m2) 23.7 (20.7, 25.4) 22.0 (20.4, 25.7) 0.46
TBSA (%) 80.0 (60.0, 82.0) 73.0 (55.0, 85.0) 0.79
Full thickness area of burn, TBSA (%) 35.0 (21.0, 49.0) 35.0 (20.5, 58.0) 0.70
ABSI 12.0 (11.0, 13.0) 13.0 (11.0, 14.0) 0.81
Aetiology    0.97
 Flame, n (%) 29 (70.7) 27 (65.9)  
 Scald, n (%) 4 (9.8) 4 (9.8)
 Electricity, n (%) 7 (17.1) 9 (22.0)
 Chemical, n (%) 1 (2.4) 1 (2.4)
Inhalation injury, n (%) 24 (58.5) 27 (65.9) 0.82
Hypovolaemic shock, n (%) 17 (41.5) 21 (51.2) 0.87
Receiving MV, n (%) 9 (22.0) 6 (14.6) 0.28
Time of randomization (hours post-burn) 20.0 (10.5, 44.8) 22.0 (14.5, 31.0) 0.37
Time of HVHF initiation (hours post-burn)   23.0 (15.5, 34.0)  
APACHE II score 11.0 (9.0, 13.0) 10.0 (9.0, 13.0) 0.51
SOFA score 3.0 (2.0, 5.0) 3.0 (1.5, 4.0) 0.69
TBIL (μmol/L) 15.2 (9.5, 26.6) 17.0 (12.4, 23.7) 0.54
BUN (mmol/L) 7.7 (4.6, 9.7) 6.5 (4.8, 8.6) 0.23
Cr (mmol/L) 88.0 (68.0, 132.0) 78.0 (65.0, 106.0) 0.38
Operation frequency in 28 days post-burn 2.0 (2.0, 2.0) 2.0 (1.0, 3.0) 0.55
Time of first excision (days post-burn) 5.0 (4.0, 7.0) 5.0 (3.5, 5.5) 0.54
Area of first excision, TBSA (%) 18.0 (11.0, 35.0) 18.5 (10.0, 33.5) 0.97
Total area of excision in 28 days post-burn, TBSA (%) 29.0 (19.0, 45.0) 34.0 (20.0, 58.0) 0.42
  1. Abbreviations: BMI Body mass index, TBSA Total burn surface area, ABSI Abbreviated Burn Severity Index, MV Mechanical ventilation, HVHF High-volume haemofiltration, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, TBIL Serum total bilirubin, BUN Blood urea nitrogen, Cr Serum creatinine
  2. Data are presented as mean ± SD, medians (with 25th and 75th quantiles) or percentages. All patients were included in summary tables via the intention-to-treat principle