Table 1 Demographic and clinical characteristics of patients
Patient Characteristic | Preintervention cohort (n = 1352) | Postintervention cohort (n = 1276) | P |
|---|---|---|---|
General data | |||
Age (years), mean (SD) | 64.3 (15.3) | 63.8 (15.1) | 0.400 |
Sex (male), n (%) | 858 (63.5) | 824 (64.6) | 0.552 |
APACHE II, mean (SD) | 22.5 (8.1) | 21.4 (8.0) | 0.001 |
SOFA, mean (SD) | 8.7 (3.5) | 8.5 (3.5) | 0.102 |
Charlson, mean (SD) | 2.7 (2.3) | 2.7 (2.3) | 0.391 |
Source of sepsis, n (%) 0.018 | |||
Pneumonia | 454 (33.6) | 403 (31.6) | |
Acute abdominal infection | 452 (33.4) | 431 (33.8) | |
Urinary tract infection | 229 (16.9) | 209 (16.4) | |
Soft-tissue infection | 82 (6.1) | 98 (7.7) | |
Meningitis | 26 (1.9) | 43 (3.4) | |
Catheter-related bacteremia | 30 (2.2) | 19 (1.5) | |
Other infections | 79 (5.8) | 73 (5.7) | |
Type of infection, n (%) 0.013 | |||
Community | 802 (59.3) | 835 (65.4) | |
Nosocomial | 302 (22.3) | 249 (19.5) | |
ICU | 65 (4.8) | 51 (4) | |
Healthcare-related | 183 (13.5) | 141 (11.1) | |
Diagnosis on admission, n (%) 0.817 | |||
Medical | 950 (70.3) | 891 (69.8) | |
Urgent surgical | 318 (23.5) | 311 (24.4) | |
Non-urgent surgical | 84 (6.2) | 74 (5.8) | |