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Table 2 Laboratory parameters on admission to ICU, day 1

From: Symmetrical (SDMA) and asymmetrical dimethylarginine (ADMA) in sepsis: high plasma levels as combined risk markers for sepsis survival

Parameter

All patients

Survivors

28 days

Non-survivors

28 days

P valuea

SDMA, μmol/L

0.93 (0.65–1.34)

0.82 (0.60–1.15)

1.14 (0.88–1.52)

0.002*

ADMA, μmol/L

0.77 (0.60–0.97)

0.73 (0.60–0.90)

0.93 (0.63–1.34)

0.016*

Leukocytes, ×109/L

12.6 (7.5–18.9)

12.8 (9.4–19.2)

12.3 (6.2–18.2)

0.205

C-reactive protein, mg/L

186.5 (124.0–243.8)

182.0 (97.5–248.0)

195.0 (130.0–243.0)

0.516

Procalcitonin, μg/L

2.25 (0.70–8.25)

1.49 (0.51–6.66)

6.29 (1.19–19.64)

0.003*

Interleukin-6, ng/L

241 (79–614)

216 (61–554)

278 (111–1000)

0.075

Lactate, mmol/L

1.1 (0.8–1.8)

1.0 (0.8–1.5)

1.2 (0.9–2.4)

0.081

Creatinine, mg/dL

1.2 (0.8–2.3)

0.6 (0.7–1.9)

1.7 (1.1–2.6)

0.009*

Bilirubin, mg/dL

0.7 (0.3–1.5)

0.6 (0.3–1.0)

1.4 (0.6–3.2)

< 0.001*

Platelets, ×109/mL

183 (93–280)

199 (124–290)

107 (40–274)

0.005*

  1. Data are presented as median (interquartile range, IQR)
  2. SDMA symmetric dimethylarginine, ADMA asymmetric dimethylarginine
  3. aNon-parametric Mann-Whitney U test comparing 28-day survivors with non-survivors
  4. *Statistically significant
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