Skip to main content

Table 2 Patient characteristics

From: Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data

Variable Missing data, n (%) Overall population (n = 7515) Neutropenic patients (n = 1702)a Non-neutropenic patients (n = 5810)a P
value
Age (years) 15 (0.2%) 60 (49–69) 55 (41–64) 61 (51–70) < 0.001
ICU admission year 0 2007 (2004–2010) 2008 (2005–2010) 2007 (2004–2010) < 0.001
Underlying malignancy
 Solid tumors 0 (0%) 3366 (44.8%) 232 (13.6%) 3131 (53.9%) < 0.001
 Hematological malignancy 0 (0%) 4149 (55.2%) 1470 (86.4%) 2679 (46.1%) < 0.001
 Allogeneic HSCT 0 (0%) 439 (5.8%) 186 (10.9%) 253 (4.4%) < 0.001
SAPS II 503 (6.7%) 41 (28–57) 51 (34–68) 39 (26–54) < 0.001
Organ support at ICU admission
 Mechanical ventilation 1 (0%) 3804 (50.6%) 964 (56.6%) 2839 (48.9%) < 0.001
 Vasopressors 0 (0%) 3084 (41%) 954 (56.1%) 2129 (36.6%) < 0.001
 Renal replacement therapy 58 (0.8%) 1201 (16%) 386 (22.7%) 815 (14%) < 0.001
Mortality 2 (0%) 3538 (47.1%) 1021 (60%) 2517 (43.3%) < 0.001
  1. HSCT hematopoietic stem cell transplantation, SAPS Simplified Acute Physiology Score, ICU intensive care unit
  2. aData on neutropenia unavailable in three patients (0.03%)