Table 1 General characteristics of the septic shock and the control groups
From: Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
Variables | Septic shock (n = 20) | Control (n = 10) | p | |
|---|---|---|---|---|
Age, years | 71 (51–84) | 50 (42–58) | 0.02 | |
Ratio, male/female | 12/8 | 8/2 | 0.27 | |
BMI, kg.m− 2 | 27 (22–31) | 25 (22–29) | 0.75 | |
SAPS II | 47 (59–75) | 38 (31–44) | 0.001 | |
SOFA | 8 (7–11) | 5 (4–6) | 0.003 | |
Pathology, n | Peritonitis | 13 | – | |
Pneumonia | 3 | – | ||
Fasciitis | 3 | – | ||
Arthritis | 1 | – | ||
ICH | – | 5 | ||
TBI | – | 4 | ||
Stroke | – | 1 | ||
MAP, mmHg | 73 (67–80) | 98 (94–108) | < 0.001 | |
Heart rate, min− 1 | 103 (88–122) | 86 (67–106) | 0.04 | |
Norepinephrine, μg.kg− 1.min− 1 | 0.22 (0.13–0.53) | 0.02 (0–0.3) | 0.03 | |
Epinephrine, μg.kg− 1.min− 1 | 0 (0–0.05) | 0 (0–0) | 0.14 | |
Cardiac index, L.min−1.m− 2 | 2.4 (2–3.2) | 2.1 (2.1–3.2) | 0.31 | |
Urine output, mL.kg− 1.h− 1 | 0.4 (0.3–1.1) | 0.8 (0.3–1.4) | 0.29 | |
Lactate, mmol.L−1 | 2.6 (2–3.9) | 1.3 (0.9–1.6) | < 0.001 | |
Urea, mmol.L−1 | 14.1 (9.4–18.5) | 6 (4–8) | 0.001 | |
Creatinine, μmol.L−1 | 152 (110–229) | 57 (51–77) | < 0.001 | |
PaO2/FiO2 ratio | 212 (160–276) | 339 (270–416) | 0.007 | |
Doppler resistivity index | 0.74 (0.68–0.79) | 0.66 (0.55–0.74) | 0.06 | |
Mortality at 72 h, n (%) | 4 (20) | 2(20) | 0.23 | |
ICU mortality, n (%) | 9 (45) | 3 (30) | 0.43 | |