Table 1 Systemic haemodynamics and flow density of retina at baseline, during progressive haemorrhage, and after resuscitation
Time point | |||||
|---|---|---|---|---|---|
Parameter (unit) | Baseline | BL 10 ml∙kg− 1 | BL 20 ml∙kg− 1 | BL 30 ml∙kg− 1 (haemorrhagic shock) | Resuscitation |
MAP (mmHg) | 117 (108; 122) | 80 (74; 98) | 44 (37; 72) | 33 (30; 38)* | 93 (76; 100) |
HR (1∙min−1) | 86 (85; 94) | 98 (84; 108) | 107 (77; 118) | 107 (92; 131) | 128 (112; 139)* |
CI (L∙min−1∙m− 2) | 2.5 (2.2; 2.7) | 1.5 (1.4; 1.6) | 1.2 (1.0; 1.9) | 1.1 (0.8; 1.2) | 3.0 (2.7; 3.8)# |
CVP (mmHg) | 3 (1; 10) | 6 (3; 9) | 2 (0; 11) | 0 (0; 6) | 5 (1; 9) |
SVI (ml∙m−2) | 20 (22; 41) | 17 (15; 23) | 13 (9; 18) | 11 (6; 21) | 24 (22; 24) |
Retinal microcirculation (OCT-A) | |||||
Flow densityWF (%) | 44.7 (40.3; 50.5) | 44.1 (36.5; 49.7) | 38.7 (22.2; 44.1) | 34.5 (32.8; 40.4)* | 46.9 (41.7; 50.7)# |
Flow densityCentral (%) | 45.2 (36.7; 48.6) | 43.4 (34.3; 46.4) | 39.2 (21.3; 42.2)§ | 32.5 (32.2; 40.0)§ | 48.6 (38.4; 50.3) |