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Table 4 Primary outcome

From: Effect of postoperative goal-directed therapy in cancer patients undergoing high-risk surgery: a randomized clinical trial and meta-analysis

Variable

GDHT group

Usual care group

Absolute difference (95% CI)

p

(n = 64)

(n = 64)

Composite endpoint

53 (40–66)

44 (31–57)

9.4 (−7.8 to 25.8)

0.3

 Mortality

14 (7–25)

9 (4–19)

4.7 (−6.9 to 16.4)

0.4

 Stroke

0 (0–6)

2 (0–8)

−1.6 (−8.3 to 4.2)

0.9

 AKI

51 (36–61)

39 (27–52)

9.4 (− 7.6 to 25.6)

0.2

 ARDS

5 (2–15)

2 (0–8)

4.7 (−3.1 to 13.5)

0.4

 Acute myocardial infarction

2 (0–8)

5 (0.9–13)

−3.1 (− 11.4 to 4.3)

0.6

 Acute heart failure

0 (0–6)

2 (0–8)

−1.6 (− 8.3 to 4.2)

0.5

 Mesenteric ischemia

2 (0–8)

0 (0–6)

1.6 (−4.2 to 8.3)

0.9

 Peripheral vascular ischemia

0 (0–6)

3 (0.3–11)

− 3.1 (− 10.7 to 3.0)

0.5

 Pulmonary embolism

0 (0–6)

0 (0–6)

 Deep wound infection

3 (0.3–11)

8 (3–17)

−4.7 (− 14.2 to 4.1)

0.4

 Reoperation

8 (3–17)

5 (0.9–13)

3.1 (− 6.2 to 12.8)

0.7

  1. Data presented as % (95% CI)
  2. GDT goal-directed hemodynamic therapy, CI confidence interval, AKI acute kidney injury, ARDS acute respiratory distress syndrome