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Table 5 Linear regression model limited to cases with one pathogen group and one focus of infection

From: Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

Variable

Regression coefficient

95% CI

p value

Multiplier

(95% CI)

Staphylococcus spp.

0.00

(− 0.22 to 0.21)

1.0

1.0 (0.6–1.6)

Streptococcus spp.

0.50

(0.26–0.74)

< 0.001

3.2 (1.8–5.5)

Enterococcus spp.

0.06

(−0.18 to 0.31)

0.6

1.1 (0.7–2.0)

Escherichia coli

0.50

(0.29–0.72)

< 0.001

3.2 (1.9–5.2)

Enterobacteriaceae, other

0.49

(0.26–0.72)

< 0.001

3.1 (1.8–5.2)

Pseudomonas spp.

0.04

(− 0.3 to 0.37)

0.8

1.1 (0.5–2.3)

Candida spp.

Reference

  

Reference

Respiratory

− 0.01

(− 0.14 to 0.12)

0.9

1 (0.7–1.3)

Abdominal

0.27

(0.14–0.41)

< 0.001

1.9 (1.4–2.6)

Urogenital

0.32

(0.17–0.47)

< 0.001

2.1 (1.5–3.0)

Bones/soft tissue

Reference

  

Reference

Intercept

0.63

(0.41–0.86)

< 0.001

4.3 (2.6–7.2)

  1. Stepwise linear regression model for influence of pathogens in blood culture and focus of infection on logPCT (p < 0.001 for both steps) limited to 1146 cases with one pathogen group detected in blood culture and one focus of infection; adjusted R2 = 0.18; effect of the interaction term not significant (p = 0.13) and it was omitted from final model
  2. After reversal of the logarithmic transformation, the multiplier equals 10regression coefficient, resulting in PCTpredicted = 4.3 × pathogen × focus × error
  3. CI confidence interval, PCT procalcitonin