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Table 3 Test performance of procalcitonin for prediction of Gram-negative bacteremia

From: Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

Classification

Optimal cutoff (ng/ml)

SENS

SPEC

PPV

NPV

PLR

NLR

ACC

Gram-negative bacteremia vs

Gram-positive/candidemia

17.5

0.59

0.70

0.61

0.68

1.98

0.59

0.65

Gram-negative bacteremia vs

all other blood culture results

10

0.69

0.65

0.33

0.9

1.97

0.47

0.66

  1. Optimal cutoff values derived from receiver operating characteristics by Youden’s index and sensitivity (SENS), specificity (SPEC), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (PLR), negative likelihood ratio (NLR) and accuracy (ACC) calculated from the resulting 2 × 2 tables